Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

CAS Number: 144164-11-4

Molecular Formula: C23H27N3O3S

Purity: Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate 95% purity

About Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate (CAS 155213-67-5) represents a critical chiral building block in the high purity fine chemicals sector, specifically utilized for the synthesis of advanced protease inhibitors within the API intermediates market. This Ritonavir intermedia...

Synonyms

144164-11-4
Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
(2S,3S,5S)-5-AMINO-2-(N-((5-THIAZOLYL)-METHOXYCARBONYL)AMINO)-1,6-DIPHENYL-3-HYDROXYHEXANE
2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane

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Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Specifications

CAS Number

144164-11-4

Molecular Formula

C23H27N3O3S

Molecular Weight

425.54 g/mol

IUPAC Name

1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate

Canonical SMILES

C1=CC=C(C=C1)CC(CC(C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)O)N

InChI Key

HBPTXDXGWDVDON-BVSLBCMMSA-N

InChI

InChI=1S/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1

HSN No

29420090

CAS Number

144164-11-4

Molecular Formula

C23H27N3O3S

Molecular Weight

425.54 g/mol

IUPAC Name

1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate

Canonical SMILES

C1=CC=C(C=C1)CC(CC(C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)O)N

InChI Key

HBPTXDXGWDVDON-BVSLBCMMSA-N

InChI

InChI=1S/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1

HSN No

29420090

Molecular Weight

425.54 g/mol

Purity

Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate 95% purity

Antiviral Agent

A potent HIV protease inhibitor used as a core component of highly active antiretroviral therapy (HAART) to prevent viral replication and manage HIV-1 infection in adults and pediatric patients

Pharmacokinetic Enhancer

A critical cytochrome P450 3A4 (CYP3A4) inhibitor utilized at low doses to boost the plasma concentrations and efficacy of other protease inhibitors and antiviral medications

COVID-19 Therapeutic

An essential boosting component co-packaged with nirmatrelvir or simnotrelvir for the treatment of mild-to-moderate COVID-19 in high-risk patients

Pharmaceutical Intermediate

A complex peptidomimetic building block used in the synthesis of specialized antiviral compounds and as a research tool in oncology and cytochrome P450 studies.

144164-11-4
Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
(2S,3S,5S)-5-AMINO-2-(N-((5-THIAZOLYL)-METHOXYCARBONYL)AMINO)-1,6-DIPHENYL-3-HYDROXYHEXANE
2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane