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Tetrahydrofuran (CAS NO : 109-99-9)

Tetrahydrofuran (CAS No: 109-99-9) is increasingly pivotal in the API intermediates market, where its high dielectric constant and aprotic nature facilitate complex custom synthesis services for active pharmaceutical ingredients. 1,4-Epoxybutane serves as a high purity fine chemicals medium for the production of pharmaceutical-grade polymers and specialized reaction solvents, requiring 99% purity to ensure minimal side-chain contamination in sensitive drug formulations. Oxolane is currently undergoing global sourcing shifts as the CDMO growth sector demands a reliable bulk chemical supplier capable of navigating tightening REACH and OSHA regulatory compliance while supporting the large-scale production of spandex and polyurethane elastomers. As globally established Tetrahydrofuran supplier, we ensure dependable supply, consistent quality, and complete regulatory documentation, including CoA and TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination.

Tetrahydrofuran

Tetrahydrofuran (CAS No: 109-99-9) is increasingly pivotal in the API intermediates market, where its high dielectric constant and aprotic nature facilitate complex custom synthesis services for active pharmaceutical ingredients. 1,4-Epoxybutane serves as a high purity fine chemicals medium for the production of pharmaceutical-grade polymers and specialized reaction solvents, requiring 99% purity to ensure minimal side-chain contamination in sensitive drug formulations. Oxolane is currently undergoing global sourcing shifts as the CDMO growth sector demands a reliable bulk chemical supplier capable of navigating tightening REACH and OSHA regulatory compliance while supporting the large-scale...

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Chemical Properties & Specifications

Applications of Tetrahydrofuran

Polymer Chemistry

An important precursor and catalyst medium used in the synthesis of polymers such as polytetramethylene ether glycol (PTMEG) and polyurethane

Industrial Solvent

A versatile aprotic solvent utilized to dissolve and bond polyvinyl chloride (PVC) plastics, varnishes, and industrial resins

Reaction Medium

A moderately polar laboratory solvent frequently applied in organic synthesis, organometallic chemistry, and Grignard reactions

Pharmaceutical Synthesis

A chemical reaction solvent used for manufacturing various drugs, steroids, and hormone formulations

Have Questions About Tetrahydrofuran?
We've Got Answers.

Tetrahydrofuran is a stable, colorless, and volatile cyclic ether with the molecular formula C4H8O, known for its low viscosity and excellent solvency

it primarily serves as a versatile solvent and reaction medium in chemical synthesis, and is used as a starting material to produce polymers like polytetramethylene ether glycol

This compound is universally utilized across various industries including polymers, plastics, adhesives, coatings, textiles, pharmaceuticals, printing inks, and electronics

It is commonly used in vinyl and epoxy adhesives, surface coatings, PVC pipe cements, varnishes, cleaning agents, and mobile phases for chromatography applications

Standard specifications include CAS number 109-99-9, high purity assay (typically min 99.0% or 99.95%), specific gravity/density around 0.887-0.89 g/cm3, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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