Pyrrolo[2,1-f][1,2,4] triazin-4-amine

CAS Number: 159326-68-8

Molecular Formula: C6H6N4

About Pyrrolo[2,1-f][1,2,4] triazin-4-amine

Pyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 159326-68-8 serves as a critical bridgehead nitrogen heterocycle for the API intermediates market, particularly in the synthesis of next-generation kinase inhibitors and antiviral C-nucleosides like Remdesivir. Pyrrolotriazin-4-amine is increasingly sought from any high purity f...

Pyrrolo[2,1-f][1,2,4] triazin-4-amine Specifications

CAS Number

159326-68-8

Molecular Formula

C6H6N4

Molecular Weight

134.14 g/mol

IUPAC Name

pyrrolo[2,1-f][1,2,4]triazin-4-amine

Canonical SMILES

C1=CN2C(=C1)C(=NC=N2)N

InChI Key

VSPXQZSDPSOPRO-UHFFFAOYSA-N

PubChem CID

10441749

CAS Number

159326-68-8

Molecular Formula

C6H6N4

Molecular Weight

134.14 g/mol

IUPAC Name

pyrrolo[2,1-f][1,2,4]triazin-4-amine

Canonical SMILES

C1=CN2C(=C1)C(=NC=N2)N

InChI Key

VSPXQZSDPSOPRO-UHFFFAOYSA-N

PubChem CID

10441749

Molecular Weight

134.14 g/mol

Physical appearance

White to orange to green powder to crystal

Pharmaceutical Intermediate

A key building block and regulatory starting material used in the synthesis of the antiviral drug remdesivir for treating COVID-19 and other viral infections

Antineoplastic Agent

A privileged heterocyclic scaffold utilized in the development of kinase inhibitors such as avapritinib and rogaratinib for cancer treatment

Research Tool

A versatile nitrogen-fused heterocycle employed in medicinal chemistry for the synthesis of bioactive molecules and the study of phosphatidylinositol-3 kinase (PI3K) signaling pathways

Chemical Building Block

An organic intermediate used in academic and industrial research for the synthesis of complex N-heterocyclic compounds through functionalization and coupling reactions.