N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide

CAS Number: 2121561-39-3

Molecular Formula: C19H19N3O3

Purity: N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide 95.00% purity

About N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide

N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (CAS 2121561-39-3) represents a vital high-purity fine chemical within the global API intermediates market, primarily utilized as a strategic precursor for the synthesis of Belumosudil, a kinase inhibitor for chronic graft-versus-host disease. Belumos...

Synonyms

2121561-39-3
N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide
N-Isopropyl-2-[3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]acetamide
SCHEMBL26120225
SY318037

N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide Specifications

CAS Number

2121561-39-3

Molecular Formula

C19H19N3O3

Molecular Weight

337.38 g/mol

IUPAC Name

2-[3-(4-oxo-3H-quinazolin-2-yl)phenoxy]-N-propan-2-ylacetamide

Canonical SMILES

CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=O)N2

InChI Key

GCQOPGCYUDSLFP-UHFFFAOYSA-N

InChI

InChI=1S/C19H19N3O3/c1-12(2)20-17(23)11-25-14-7-5-6-13(10-14)18-21-16-9-4-3-8-15(16)19(24)22-18/h3-10,12H,11H2,1-2H3,(H,20,23)(H,21,22,24)

PubChem CID

168448038

HSN No

29339900

CAS Number

2121561-39-3

Molecular Formula

C19H19N3O3

Molecular Weight

337.38 g/mol

IUPAC Name

2-[3-(4-oxo-3H-quinazolin-2-yl)phenoxy]-N-propan-2-ylacetamide

Canonical SMILES

CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=O)N2

InChI Key

GCQOPGCYUDSLFP-UHFFFAOYSA-N

InChI

InChI=1S/C19H19N3O3/c1-12(2)20-17(23)11-25-14-7-5-6-13(10-14)18-21-16-9-4-3-8-15(16)19(24)22-18/h3-10,12H,11H2,1-2H3,(H,20,23)(H,21,22,24)

PubChem CID

168448038

HSN No

29339900

Molecular Weight

337.38 g/mol

Purity

N-Isopropyl-2-(3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide 95.00% purity

Pharmaceutical Intermediate

A key intermediate used in the synthesis of Belumosudil, a kinase inhibitor indicated for the treatment of chronic graft-versus-host disease

Organic Synthesis Building Block

A functionalized quinazolinone derivative utilized as a starting material for the development of complex molecules and potential EGFR kinase inhibitors in medicinal chemistry research.