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N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

CAS Number: 444731-74-2

Molecular Formula: C13H12ClN5

Purity: N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine 95% purity

About N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine (CAS 444731-74-2) acts as a pivotal heterocyclic building block within the high-growth API intermediates market, primarily utilized for the advanced synthesis of Pazopanib, a potent multi-targeted tyrosine kinase inhibitor. Pazopanib Pyrimidine Impurity serves ...

Synonyms

  • 444731-74-2
  • N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYL-2H-INDAZOL-6-AMINE
  • N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine
  • 6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole
  • N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYLINDAZOL-6-AMINE

N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine Specifications

CAS Number
444731-74-2
Molecular Formula
C13H12ClN5
Molecular Weight
273.72 g/mol
IUPAC Name
N-(2-chloropyrimidin-4-yl)-2,3-dimethylindazol-6-amine
Canonical SMILES
CC1=C2C=CC(=CC2=NN1C)NC3=NC(=NC=C3)Cl
InChI Key
SCUMWVJJSLLWHQ-UHFFFAOYSA-N
InChI
InChI=1S/C13H12ClN5/c1-8-10-4-3-9(7-11(10)18-19(8)2)16-12-5-6-15-13(14)17-12/h3-7H,1-2H3,(H,15,16,17)
PubChem CID
11637631
HSN No
2933990090
Molecular Weight
273.72 g/mol
Purity
N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine 95% purity

Pharmaceutical Intermediate

An important building block and precursor utilized in the synthesis of Pazopanib, a multi-tyrosine kinase inhibitor used as an antineoplastic agent for the treatment of advanced renal cell carcinoma

Heterocyclic Building Block

A functionalized indazole and pyrimidine derivative employed in organic synthesis for the development of complex molecules and active pharmaceutical ingredients in medicinal chemistry research

Laboratory Reagent

A high-purity chemical compound suitable for R&D applications, including enzymatic assays and kinase inhibition studies in biotechnology and life science industries.

  1. 444731-74-2
  2. N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYL-2H-INDAZOL-6-AMINE
  3. N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine
  4. 6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole
  5. N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYLINDAZOL-6-AMINE

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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