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1-(Mercaptomethyl)cyclopropaneacetic acid is a key intermediate in the synthesis of Montelukast, a leukotriene receptor antagonist used for the treatment of asthma and allergic rhinitis. This compound features a cyclopropane ring with a mercaptomethyl group, playing a crucial role in building the active pharmaceutical ingredient. Also known as 1-(MERCAPTOMETHYL) CYCLOPROPANE ACETIC ACID
![Montelukast intermediate (2-[1-(Mercaptomethyl)cyclopropyl] acetic acid)](/_next/image?url=https%3A%2F%2Fcdn.scimplify.com%2Fproducts%2Fimages%2F66d1641935e319a86ad15592%2Ff40a27a6-d4ff-4d2f-b18f-52597020ed39.jpg&w=3840&q=75)
1-(Mercaptomethyl)cyclopropaneacetic acid is a key intermediate in the synthesis of Montelukast, a leukotriene receptor antagonist used for the treatment of asthma and allergic rhinitis. This compound features a cyclopropane ring with a mercaptomethyl group, playing a crucial role in building the active pharmaceutical ingredient. Also known as 1-(MERCAPTOMETHYL) CYCLOPROPANE ACETIC ACID
Chemical Properties & Specifications
Corrosive to metals: Category 1 Acute toxicity (Oral, Dermal): Category 4 Skin corrosion: Category 1B Skin sensitization: Category 1 Hazardous to the aquatic environment (Chronic): Category 2
Acute oral toxicity-Category 4 Acute dermal toxicity-Category 4 Skin Corrosion/Irritation-Category 1 B Serious Eye Damage/Eye Irritation-Category 1 Skin Sensitization-Category 1 Specific target organ toxicity (single exposure)-Category 3 Target Organs - Respiratory system.
P234: Keep only in original packaging. P260: Do not breathe dust/fume/gas/mist/vapors/spray. P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P272: Contaminated work clothing should not be allowed out of the workplace. P273: Avoid release to the environment. P280: Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331+P310: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER/doctor. P303+P361+P353+P310+P363: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. Immediately call a POISON CENTER/doctor. Wash contaminated clothing before reuse. P304+P340+P310: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305+P351+P338+P310: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Immediately call a POISON CENTER/doctor. P390: Absorb spillage to prevent material damage. P391: Collect spillage. P405: Store locked up. P406: Store in a corrosion-resistant container with a resistant inner liner. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.
Serves as a crucial intermediate in the synthesis of Montelukast, aiding in the production of medications for asthma and allergic rhinitis.
It is utilized in the synthesis of certain pesticides and fungicides, contributing to crop protection by targeting specific plant pathogens.
Researchers employ this compound to study cyclopropyl-containing molecules, aiding in the development of new therapeutic agents with unique mechanisms of action.
Store at room temperature (typically 15–30°C or 59–86°F).
Keep in a dry, well-ventilated area away from moisture and incompatible substances.
Store in original, tightly sealed containers to prevent oxidation and degradation.
Available in 1 kg, 5 kg, 10 kg, and 25 kg containers. Custom packaging available upon request.
This compound is a key intermediate in the synthesis of Montelukast, a medication used to treat asthma and allergic rhinitis.
It provides the structural foundation for Montelukast, contributing to the cyclopropane moiety essential in the API's mechanism of action.
Its stable properties and controlled reactivity make it an ideal intermediate for Montelukast synthesis, ensuring high yield and purity.
The highest demand is observed in North America, Europe, and Asia, where Montelukast is widely used for asthma management.
This intermediate is regulated under pharmaceutical import/export guidelines, requiring compliance with GMP and ISO standards in key markets.
