Minoxidil

CAS Number: 38304-91-5

Molecular Formula: C9H15N5O

UNII Code: 5965120SH1INDIA & EU Approved : Topical useFDA Approved : Topical and Oral useCHEBI: 6942Trusted Choice : Treating androgenetic alopeciaTopical ApplicationAimed cosmetic formulation

About Minoxidil

Minoxidil is a pyrimidine derivative originally developed as an oral antihypertensive agent. It is now widely used in topical formulations to treat androgenetic alopecia and other forms of hair loss. Minoxidil acts as a potassium channel opener, leading to vasodilation and improved blood flow to hair follicles, thereby...

Minoxidil Specifications

CAS Number

38304-91-5

Molecular Formula

C9H15N5O

IUPAC Name

2,6-Diamino-4-(piperidin-1-yl)pyrimidine 1-oxide or 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

Canonical SMILES

Nc1cc(nc(N)[n+]1[O-])N2CCCCC2

InChI Key

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

PubChem CID

4201

UNII Code

5965120SH1

ChEBI ID

6942

CAS Number

38304-91-5

Molecular Formula

C9H15N5O

IUPAC Name

2,6-Diamino-4-(piperidin-1-yl)pyrimidine 1-oxide or 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

Canonical SMILES

Nc1cc(nc(N)[n+]1[O-])N2CCCCC2

InChI Key

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

PubChem CID

4201

UNII Code

5965120SH1

ChEBI ID

6942

Physical State

White to off-white crystalline powder

Solubility

Soluble in water, ethanol, and methanol

Melting Point

Approximately 248°C

Boiling Point

351.7±45.0°C at 760 mmHg

Density

1.5±0.1 g/mL

pKa

4.61

Log P (Octanol/Water)

1.24

Water Solubility

1.49 mg/mL at 25°C

Flash Point

166.5±28.7°C

Refractive Index

1.724

Vapor Pressure

0.0±1.8 mmHg at 25°C

(H) Statement

H302: Harmful if swallowed H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation

(P) Statement

P261: Avoid breathing dust/fume/gas/mist/vapors/spray P264: Wash hands thoroughly after handling P270: Do not eat, drink, or smoke when using this product P280: Wear protective gloves/eye protection/face protection P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell P302+P352: IF ON SKIN: Wash with plenty of soap and water P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P312: Call a POISON CENTER or doctor if you feel unwell P321: Specific treatment (see on this label) P330: Rinse mouth P332+P313: If skin irritation occurs: Get medical advice/attention P337+P313: If eye irritation persists: Get medical advice/attention P362: Take off contaminated clothing and wash before reuse P403+P233: Store in a well-ventilated place. Keep container tightly closed P405: Store locked up P501: Dispose of contents/container in accordance with local/regional/national/international regulationsHazard