LOPERAMIDE HYDROCHLORIDE

CAS Number: 34552-83-5

Molecular Formula: C29H34Cl2N2O2

Purity: Loperamide Hydrochloride 99% purity

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About LOPERAMIDE HYDROCHLORIDE

Loperamide Hydrochloride (CAS 34552-83-5) serves as a cornerstone in the global gastrointestinal therapeutic sector, where its role as a potent opioid-receptor agonist necessitates high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) to ensure optimal efficacy and patient safety. 4-(4-Chloro...

LOPERAMIDE HYDROCHLORIDE Specifications

CAS Number

34552-83-5

Molecular Formula

C29H34Cl2N2O2

Molecular Weight

513.51 g/mol

IUPAC Name

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride

Canonical SMILES

CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

InChI Key

PGYPOBZJRVSMDS-UHFFFAOYSA-N

HSN No

29333990

CAS Number

34552-83-5

Molecular Formula

C29H34Cl2N2O2

Molecular Weight

513.51 g/mol

IUPAC Name

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride

Canonical SMILES

CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

InChI Key

PGYPOBZJRVSMDS-UHFFFAOYSA-N

HSN No

29333990

Molecular Weight

513.51 g/mol

Purity

Loperamide Hydrochloride 99% purity

Physical appearance

White to Almost white powder to crystal

Melting Point

220-228 °C

Boiling Point

647.2 °C at 760 mmHg

Freezing point

220-228°C

logP

5.13

Precautionary Statement Codes

P264, P270, P301+P316, P321, P330, P405, and P501

Hazard Classes and Categories

Acute Tox. 3 (100%)

Antidiarrheal Agent

A synthetic mu-opioid receptor agonist used for the symptomatic relief of acute and chronic diarrhea by decreasing intestinal motility and increasing water absorption

Pharmaceutical Active Ingredient

A piperidine-derived small molecule utilized as the primary therapeutic component in the formulation of over-the-counter and prescription gastrointestinal medications

Research Tool

A high-affinity peripheral opioid agonist employed in pharmacological studies to investigate opioid receptor signaling, intestinal ion transport, and the role of P-glycoprotein in blood-brain barrier permeability