Lamivudine

CAS Number: 134678-17-4

Molecular Formula: C8H11N3O3S

Purity: 98% purity

About Lamivudine

3TC CAS 134678-17-4 is a critical nucleoside reverse transcriptase inhibitor utilised as a high purity fine chemical for the treatment of HIV-1 and chronic hepatitis B, necessitating a Pharma/API purity 99% to meet stringent pharmacopeial standards. 2',3'-dideoxy-3'-thiacytidine serves as a primary component in the API...

Synonyms

2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
BCH 189

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Lamivudine Specifications

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26 g/mol

IUPAC Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Canonical SMILES

C1=CN([C@@H]2CS[C@H](CO)O2)C(=O)N=C1N

InChI Key

JTEGQNOMFQHVDC-NKWVEPMBSA-N

PubChem CID

60825

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26 g/mol

IUPAC Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Canonical SMILES

C1=CN([C@@H]2CS[C@H](CO)O2)C(=O)N=C1N

InChI Key

JTEGQNOMFQHVDC-NKWVEPMBSA-N

PubChem CID

60825

Molecular Weight

229.26 g/mol

Purity

98% purity

Physical appearance

White to off-white crystalline solid or powder

Antiviral Agent

A nucleoside reverse transcriptase inhibitor (NRTI) primarily utilized as a cornerstone in antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV-1 and HIV-2) infections and chronic hepatitis B virus (HBV) infection in both adult and pediatric populations

Pharmaceutical Intermediate

A synthetic nucleoside analogue and cytidine derivative used as an active pharmaceutical ingredient (API) in the formulation of oral tablets and solutions, often in fixed-dose combinations with other antiretrovirals like zidovudine or abacavir

DNA Synthesis Inhibitor

A chemical tool used in molecular biology and virology research to study viral replication mechanisms through competitive inhibition of viral DNA polymerase and reverse transcriptase, leading to DNA chain termination.

2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
BCH 189