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1-Methyl-3-phenylpiperazine (CAS 5271-27-2) is a critical heterocyclic building block in the API intermediates market, primarily utilized for the synthesis of the antidepressant Mirtazapine and other complex psychoactive pharmaceuticals where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure reaction efficiency and minimize side-stream impurities. Piperazine, 1-methyl-3-phenyl- serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory standards for central nervous system (CNS) therapeutic development. 3-Phenyl-1-methylpiperazine remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing while maintaining precise chemical morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an globally established 1-Methyl-3-phenylpiperazine intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 1-Methyl-3-phenylpiperazine COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
1-Methyl-3-phenylpiperazine (CAS 5271-27-2) is a critical heterocyclic building block in the API intermediates market, primarily utilized for the synthesis of the antidepressant Mirtazapine and other complex psychoactive pharmaceuticals where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure reaction efficiency and minimize side-stream impurities. Piperazine, 1-methyl-3-phenyl- serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory standards for cent...
Chemical Properties & Specifications
P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, and P501
Acute Tox. 4 (100%)
Skin Irrit. 2 (100%)
A key building block and essential starting material used in the synthesis of the antidepressant drug Mirtazapine and other tetracyclic medicinal compounds
A reagent utilized in academic and industrial research for organic synthesis, specifically in the development of substituted piperazine derivatives and complex bioactive molecules.
l-Methyl 3-Phenyl Piperazine, also known as 1-Methyl-3-phenylpiperazine or MePP, is a phenylpiperazine derivative that serves as a key chemical intermediate, most notably as a precursor in the synthesis of the antidepressant drug Mirtazapine
This compound is primarily utilized in the pharmaceutical industry for drug synthesis and neurological research, as well as in the agrochemical and specialty chemical sectors as a building block for organic synthesis
It is soluble in acetone, ethanol, and toluene, and sparingly soluble in DMSO and PBS (pH 7.2), making it suitable for liquid-phase organic synthesis and analytical applications
Standard specifications include CAS number 5271-27-2, high purity (typically ≥98%), a melting point of 58-62°C, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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