HBTU

CAS Number: 94790-37-1

Molecular Formula: C11H16F6N5OP

Purity: HBTU 98% purity

HBTU supplierbuy HBTU peptide coupling reagentpharmaceutical grade HBTUHBTU priceindustrial grade biochemical intermediateswholesale 94790-37-1 chemical synthesis

About HBTU

O,O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate (CAS 94790-37-1) represents a cornerstone in the API intermediates market, serving as a high-performance peptide coupling reagent essential for the synthesis of complex macrocyclic pharmaceuticals where high purity fine chemicals (Pharma/API purity ...

Variants

2-(1h-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

MBC-II (4-Methoxybenzyl chloride)

CAS: 94790-37-1

HBTU Specifications

CAS Number

94790-37-1

Molecular Formula

C11H16F6N5OP

Molecular Weight

379.25 g/mol

IUPAC Name

[benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium hexafluorophosphate

Canonical SMILES

CN(C)C(=[N+](C)C)ON1C2=CC=CC=C2N=N1.F[P-](F)(F)(F)(F)F

InChI Key

UQYZFNUUOSSNKT-UHFFFAOYSA-N

InChI

InChI=1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

EINECS Number

423-020-5

MDL Number

MFCD00075445

HSN No

29339900

CAS Number

94790-37-1

Molecular Formula

C11H16F6N5OP

Molecular Weight

379.25 g/mol

IUPAC Name

[benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium hexafluorophosphate

Canonical SMILES

CN(C)C(=[N+](C)C)ON1C2=CC=CC=C2N=N1.F[P-](F)(F)(F)(F)F

InChI Key

UQYZFNUUOSSNKT-UHFFFAOYSA-N

InChI

InChI=1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

EINECS Number

423-020-5

MDL Number

MFCD00075445

HSN No

29339900

Molecular Weight

379.25 g/mol

Purity

HBTU 98% purity

Melting Point

200 °C (dec.)

Freezing point

200 °C

Density

1.5095 g/cm3

logP

3.432

Precautionary Statement Codes

P210, P240, P241, P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P332+P313, P337+P313, P362, P370+P378, P403+P233, P405, and P501

Hazard Classes and Categories

Skin Irrit. 2 (100%) Eye Irrit. 2A (100%)

Peptide Coupling Reagent

A widely utilized uronium salt reagent primarily used for the activation of free carboxylic acids to facilitate efficient amide bond formation in both solid-phase and solution-phase peptide synthesis

Organic Synthesis Building Block

A versatile coupling agent employed in the construction of complex molecules, including natural products, macrocycles, and pharmaceutical intermediates through the formation of amide and ester linkages

Bioconjugation Agent

A functional reagent used to facilitate the conjugation of carboxylic acid-containing molecules to amine-bearing biomolecules such as proteins, antibodies, and oligonucleotides

Chemical Intermediate

A critical component in the one-pot synthesis of acyl azides, ureas, and carbamates, as well as in the construction of sulfoguanidine analogs and metal-organic complexes.