Glimepiride

Glimepiride

CAS Number
93479-97-1
Molecular Formula
C24H34N4O5S
Glimepiride manufacturersbuy Glimepiride APIGlimepiride bulk supplierantidiabetic pharmaceutical gradeGlimepiride USP BP EPindustrial grade sulfonylurea chemicals

About Glimepiride

Glimepiride (CAS 93479-97-1) is a predominant second-generation sulfonylurea in the API intermediates market, essential for formulating oral solid dosage treatments for Type 2 diabetes. As a leading bulk chemical supplier, we recognize that CDMOs are increasingly focusing on high-purity fine chemicals (Pharma/API purit...

Glimepiride Specifications

CAS Number
93479-97-1
Molecular Formula
C24H34N4O5S
IUPAC NameORBotanical Name
3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
Canonical SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
InChI Key
WIGIZIANZCJQQY-RUCARUNLSA-N
InChI
InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
EINECS Number
642-221-0
MDL Number
MFCD00878417
HSN No
30049099
Molecular Weight
490.62 g/mol
Melting Point
207°C
Boiling Point
677.0±65.0 °C at 760 mmHg
Density
1.29±0.1 g/cm3
pKa
7.26
PSA
130 Ų
logP
3.9
Average mass
490.62 g/mol
Monoisotopic mass
490.22499137 Da
Molar mass
490.62 g/mol
Vapour pressure
0.0±2.2 mmHg at 25°C
Precautionary Statement Codes
P201, P202, P261, P264, P270, P271, P280, P281, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P311, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Hazard Classes and Categories
Acute Tox. 3 (37.5%) Eye Irrit. 2 (62.5%)

Type 2 Diabetes Mellitus Management

Glimepiride is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes by stimulating pancreatic beta cells to release insulin and increasing peripheral insulin sensitivity

Pharmaceutical Research and Development

This second-generation sulfonylurea is used in clinical studies and comparative trials to evaluate glycemic efficacy, cardiovascular safety, and its role as a second-line therapy in combination with metformin or insulin

Biochemical and Pharmacological Assays

Glimepiride serves as a research tool to study ATPase-dependent potassium channel blocking in pancreatic cells and to investigate extrapancreatic effects such as GLUT4 transport protein activation in fat and muscle tissues

Glimepiride FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

Rounded Top

Explore Pharmaceutical Portfolio

Calcium acetate monohydrate

CAS No 5743-26-0

Calcium acetate monohydrate

Category

Pharmaceutical Actives & Precursors

Sub-Category

Active Pharmaceutical Ingredients (APIs)

Description : Calcium acetate monohydrate (CAS No: 5743-26-0) occupies a critical position in the global speciality chemicals market, primarily driven by its dual-functional role as a high-affinity phosphate binder in pharmaceutical renal care and a versatile stabiliser in the food and beverage industry. In the pharmaceutical sector, the compound is indispensable for managing hyperphosphatemia in patients with end-stage renal disease, where its high solubility and controlled calcium release profiles are superior to traditional carbonate-based binders. Within the food science landscape, it functions as a highly effective antimicrobial and acidity regulator, particularly in the industrial bakery sector to prevent rope formation caused by Bacillus species, while also serving as a secondary calcium fortifier in functional dairy and nutraceutical products. Furthermore, the industrial application of calcium acetate monohydrate is expanding into environmental technologies, specifically in flue-gas desulphurisation and wastewater treatment, where it acts as a precise precipitant for fluoride and heavy metal removal, meeting increasingly stringent global regulatory standards for industrial discharge. As a globally established Calcium acetate monohydrate supplier with high purity levels, we ensure dependable supply, consistent quality, and complete regulatory documentation, including Calcium acetate monohydrate CoA and Calcium acetate monohydrate TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination.

View Product
Magnesium Sulphate Monohydrate

CAS No 14168-73-1

Magnesium Sulphate Monohydrate

Category

Pharmaceutical Actives & Precursors, Inorganic Chemicals

Sub-Category

Active Pharmaceutical Ingredients (APIs), Inorganic Salts

Description : We supply high-efficiency magnesium sulphate monohydrate (CAS No: 14168-73-1) archieved across international commodity exchanges as mineral kieserite, dried magnesium sulphate, and high-density granular MgSO₄·H₂O to optimise nutrient efficiency and processing yields in the global agricultural blending, polymer manufacturing, and paper pulp sectors. Perfectly enhanced for structural integrity and stable, mid-rate dissolution, our industrial-grade magnesium sulphate monohydrate provides a concentrated source of highly bioavailable magnesium and sulphur. As global agricultural supply chains move away from low-density, moisture-heavy heptahydrate salts to reduce international ocean freight overhead, blending facilities are modifying their compound infrastructure. Large-scale fertiliser producers are upgrading their dry-bulk operations by sourcing our strictly controlled, free-flowing granular monohydrate. International agribusiness networks and polymer compounders partner with us as their certified global magnesium sulphate monohydrate supplier to guarantee reliable material sizing and uninterrupted bulk allocation. As global environmental protocols demand higher nitrogen-use efficiency in commercial crops, choosing us as your primary magnesium sulphate monohydrate supplier delivers the specific chlorophyll-building block needed to accelerate plant protein synthesis. Sourcing managers can readily audit our continuous production tolerances by downloading the batch-specific Magnesium Sulphate Monohydrate COA and TDS sheets, which verify exact fractional ratios of water-soluble magnesium oxide (MgO) and sulphur (S). Reviewing our official Magnesium Sulphate Monohydrate COA and TDS documentation ensures complete regulatory compliance across border customs and establishes a clear technical baseline for continuous bulk compounding. Contact us as your dedicated magnesium sulphate monohydrate supplier to organise automated logistics routing for international procurement.

View Product
P-Nitrobenzoyl Chloride

CAS No 122-04-3

P-Nitrobenzoyl Chloride

Category

Pharmaceutical Actives & Precursors

Sub-Category

Intermediates & Precursors

Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market, primarily utilized for the synthesis of complex nitro-substituted aromatic compounds and radiopharmaceuticals for neuroimaging where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure reaction efficiency. 4-Nitrobenzoyl chloride serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory and environmental standards. 4-Nitrobenzoic acid chloride remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing of dyes and specialty polymers while maintaining precise crystalline morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting P-Nitrobenzoyl Chloride COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

View Product
3-(4 Chloro Phenyl) Glutaric Acid

CAS No 35271-74-0

Category

Pharmaceutical Actives & Precursors

Sub-Category

Active Pharmaceutical Ingredients (APIs)

Description : 3-(4-Chlorophenyl)glutaric acid (CAS 35271-74-0) is a pivotal building block in the API intermediates market, primarily serving as the essential precursor for the synthesis of the muscle relaxant Baclofen, where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are required to meet strict USP and EP quality standards. 3-(4-Chlorophenyl)pentanedioic acid functions as a high-performance intermediate in the evolving custom synthesis services landscape, as CDMOs prioritize strategic global sourcing and rigorous analytical validation to optimize reaction yields and purity profiles in large-scale pharmaceutical manufacturing. 3-(4-Cl-Phenyl)glutaric acid remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting the industry's shift toward reliable precursors that offer precise crystalline morphology and long-term stability for complex organic synthesis and agrochemical applications (Pharma/API purity 99% | General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 3-(4-Chloro Phenyl) Glutaric Acid COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

View Product