Gemcitabine

CAS Number: 95058-81-4

Molecular Formula: C9H11F2N3O4

Purity: Gemcitabine 98% purity

About Gemcitabine

Gemcitabine (CAS 95058-81-4) is a cornerstone nucleoside metabolic inhibitor in the global API intermediates market, primarily indicated as a first-line treatment for pancreatic cancer and in combination therapies for advanced ovarian and non-small cell lung cancers. Gemzar hydrochloride functions as a high-performance...

Synonyms

188011, LY
2' Deoxy 2' Difluorocytidine
2' Deoxy 2',2'' Difluorocytidine 5' O Monophosphate
2',2'-DFDC
2',2'-difluoro-2'-deoxycytidine

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Gemcitabine Specifications

CAS Number

95058-81-4

Molecular Formula

C9H11F2N3O4

Molecular Weight

263.20 g/mol

IUPAC Name

4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

HSN No

30049049

CAS Number

95058-81-4

Molecular Formula

C9H11F2N3O4

Molecular Weight

263.20 g/mol

IUPAC Name

4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

HSN No

30049049

Molecular Weight

263.20 g/mol

Purity

Gemcitabine 98% purity

Antineoplastic Agent

A pyrimidine analog antimetabolite chemotherapy drug primarily used in the treatment of various solid tumors including pancreatic, non-small cell lung, ovarian, and metastatic breast cancers by inhibiting DNA synthesis and inducing apoptosis

Pharmaceutical Intermediate

A high-purity chemical building block utilized in the synthesis of specialized nucleotide analogs and active pharmaceutical ingredients for oncological research

Radiosensitizer

A potent clinical agent used to enhance the effectiveness of radiotherapy in locally advanced cancers by sensitizing tumor cells to ionizing radiation

Research Tool

A biochemical probe employed in molecular biology and pharmacology to study pyrimidine nucleotide metabolism, deoxycytidine kinase saturation, and drug resistance mechanisms in malignant cell lines.