Fosfomycin Trometamol

CAS Number: 78964-85-9

Molecular Formula: C7H18NO7P

Single-Dose TherapyBroad-Spectrum ActivitySingle-dose regimenActive against : Gram-positive and Gram-negative bacteria(FDA) regulated for pharmaceutical applicationsEU complied for antibiotic agentsTherapeutic category: AntibioticUnder R&DGrade: In-House

About Fosfomycin Trometamol

Fosfomycin Trometamol is a broad-spectrum antibiotic used primarily in the treatment of urinary tract infections (UTIs). It functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The trometamol (tris(hydroxymethyl)aminomethane) salt form enhances its solubility and absorption when admin...

Fosfomycin Trometamol Specifications

CAS Number

78964-85-9

Molecular Formula

C7H18NO7P

Molecular Weight

259.19 g/mol

IUPAC Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid

Canonical SMILES

C[C@H]1[C@H](O1)P(=O)(O)O.C(C(CO)(CO)N)O

InChI Key

QZJIMDIBFFHQDW-LMLSDSMGSA-N

InChI

1S/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.0/s1

CAS Number

78964-85-9

Molecular Formula

C7H18NO7P

Molecular Weight

259.19 g/mol

IUPAC Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid

Canonical SMILES

C[C@H]1[C@H](O1)P(=O)(O)O.C(C(CO)(CO)N)O

InChI Key

QZJIMDIBFFHQDW-LMLSDSMGSA-N

InChI

1S/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.0/s1

Molecular Weight

259.19 g/mol

Solubility in Water

Soluble in water

Solubility in Organic Solvents

Soluble in methanol and ethanol

Appearance

Colorless to pale yellow solution

Shelf life

2 years

(H) Statements

H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.

(P) Statements

P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear protective gloves/eye protection/face protection. P302+P352: IF ON SKIN: Wash with plenty of soap and water. P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor if you feel unwell. P321: Specific treatment (see on this label). P332+P313: If skin irritation occurs: Get medical advice/attention. P337+P313: If eye irritation persists: Get medical advice/attention. P362: Take off contaminated clothing and wash before reuse. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.

Urinary Tract Infection Treatment

Fosfomycin Trometamol is commonly prescribed for the treatment of uncomplicated UTIs, offering a single-dose therapy option due to its efficacy and favorable pharmacokinetic properties. Active against a wide range of Gram-positive and Gram-negative bacteria.