Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It functions by inhibiting cyclooxygenase (COX) enzymes, leading to a decrease in prostaglandin synthesis, which mediates inflammation and pain. Etodolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. It has a role as a non-steroidal anti-inflammatory drug, a cyclooxygenase 2 inhibitor, a non-narcotic analgesic and an antipyretic. It is a monocarboxylic acid and an organic heterotricyclic compound. It's other identifier is UNII: 2M36281008.
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It functions by inhibiting cyclooxygenase (COX) enzymes, leading to a decrease in prostaglandin synthesis, which mediates inflammation and pain. Etodolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. It has a role as a non-steroidal anti-inflammatory drug, a cyclooxygenase 2 inhibitor, a non-narcotic analgesic and an antipyretic. It is a monocarboxylic acid and an organic heterotricyclic compound. It's other identifier is UNII: 2M36281008.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Acute Toxicity (Oral): Category 3 Eye Irritation: Category 2A Reproductive Toxicity: Category 2
H301: Toxic if swallowed. H319: Causes serious eye irritation. H361: Suspected of damaging fertility or the unborn child.
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P280: Wear protective gloves, clothing, and eye protection. P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. P308+P313: IF exposed or concerned: Get medical advice/attention. P405: Store locked up. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.
Used in the formulation of medications for the treatment of osteoarthritis, rheumatoid arthritis, and acute pain management.
Acts as an anti-inflammatory and analgesic agent in various pharmaceutical formulations
Store at refrigerated temperatures between 0–10°C.
Keep in a cool, dry place away from direct sunlight and moisture.
Store in tightly sealed, light-resistant containers to prevent degradation.
Available in 5 g, 25 g, and bulk quantities.
