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Triethyl Orthoformate (TEOF) is a reactive organic intermediate used extensively in organic synthesis. TEOF acts as a formylating agent and protecting group reagent for alcohols and amines, and serves as a building block for heterocyclic compounds, pharmaceuticals, and fine chemicals. Due to its low viscosity and high reactivity, Triethyl Orthoformate is ideal for condensation, acetal formation, and esterification reactions. Also referred to as OFE (ETHER), Ethylorthoformiat by TEOF manufacturers. We are among the trusted Triethyl Orthoformate (TEOF) suppliers worldwide, with reliable lead times and global supply capability.
Triethyl Orthoformate (TEOF) is a reactive organic intermediate used extensively in organic synthesis. TEOF acts as a formylating agent and protecting group reagent for alcohols and amines, and serves as a building block for heterocyclic compounds, pharmaceuticals, and fine chemicals. Due to its low viscosity and high reactivity, Triethyl Orthoformate is ideal for condensation, acetal formation, and esterification reactions. Also referred to as OFE (ETHER), Ethylorthoformiat by TEOF manufacturers. We are among the trusted Triethyl Orthoformate (TEOF) suppliers worldwide, with reliable lead times and global supply capability.
Chemical Properties & Specifications
Flammable liquid (Cat. 2), Eye Irritation (Cat. 2)
H225, H319
P210, P233, P280, P305+P351+P338
Formylation, acetalisation, and esterification in pharmaceutical and fine chemical manufacturing (Formylation agent, acetal formation, esterification reagent)
Key intermediate in heterocyclic compound synthesis and medicinal chemistry (Heterocyclic synthesis, pharma intermediate, synthetic building block)
Available in ≥99% purity, ensuring reproducibility in lab and industrial reactions
Compatible with alcohols, amines, and other nucleophiles, providing versatile synthetic pathways (Reactive intermediate, nucleophilic reactions, organic synthesis)
15–30 °C; store in dry, ventilated area
25 L HDPE or glass bottles; bulk 200 L drums
2 years under recommended storage
Palletized, shrink-wrapped; stack ≤2 drums; follow flammable chemical transport regulations
It is used as a formylating agent, protecting group reagent, and intermediate for acetal, ester, and heterocyclic compound synthesis.
No. It is strictly a chemical intermediate for laboratory and industrial synthesis.
Compatible with ethanol, ether, and other polar organic solvents. Sensitive to water.
Highly flammable; use gloves, eye protection, and handle in ventilated areas. Keep away from sparks and open flames.
Consistent technical grade quality, versatile reactive intermediate, and full documentation (CoA, SDS, ISO) for procurement and manufacturing. Is Triethyl Orthoformate compliant with international regulations? Yes, REACH-registered and TSCA-compliant. Documentation is provided for safe international trade.
Yes, REACH-registered and TSCA-compliant. Documentation is provided for safe international trade.
