Ethyl orthoformate (Triethyl orthoformate)

Ethyl orthoformate (Triethyl orthoformate)

CAS Number
122-51-0
Molecular Formula
C7H16O3
Formylation & Syntheic AgentHeterocyclic synthesisReactive & Pharma intermediateOrganic ReagentSynthetic building blockREACH (EU), TSCA (US) EPA RegisteredISO 9001 Plant TEOF

About Ethyl orthoformate (Triethyl orthoformate)

Triethyl Orthoformate (TEOF) is a reactive organic intermediate used extensively in organic synthesis. TEOF acts as a formylating agent and protecting group reagent for alcohols and amines, and serves as a building block for heterocyclic compounds, pharmaceuticals, and fine chemicals. Due to its low viscosity and high ...

Synonyms

  • Triethyl orthoformate
  • 122-51-0
  • Triethoxymethane
  • ETHYL ORTHOFORMATE
  • diethoxymethoxyethane

Ethyl orthoformate (Triethyl orthoformate) Specifications

CAS Number
122-51-0
Molecular Formula
C7H16O3
Molecular Weight
148.20 g/mol
IUPAC Name
diethoxymethoxyethane
Canonical SMILES
CCOC(OCC)OCC
InChI Key
GKASDNZWUGIAMG-UHFFFAOYSA-N
InChI
1S/C7H16O3/c1-4-8-7(9-5-2)10-6-3/h7H,4-6H2,1-3H3
EINECS Number
204-550-4
MDL Number
MFCD00001545
UNSPSC Code
12352200
HSN No
2915.90.99 / 2915.90.90
Molecular Weight
148.20 g/mol
XLogP3
1.2
Exact Mass
148.109944368 Da
Boiling Point
103 °C at 10 mmHg (vacuum)
Flash Point
39 °C
GHS Classification
Flammable liquid (Cat. 2), Eye Irritation (Cat. 2)
(H) Statement Codes
H225, H319
(P) Statement Codes
P210, P233, P280, P305+P351+P338

Organic Synthesis Reagent

Formylation, acetalisation, and esterification in pharmaceutical and fine chemical manufacturing (Formylation agent, acetal formation, esterification reagent)

Pharmaceutical Intermediates

Key intermediate in heterocyclic compound synthesis and medicinal chemistry (Heterocyclic synthesis, pharma intermediate, synthetic building block)

High Purity & Technical Grade & organic reagent

Available in ≥99% purity, ensuring reproducibility in lab and industrial reactions

Reactive Functional Utility

Compatible with alcohols, amines, and other nucleophiles, providing versatile synthetic pathways (Reactive intermediate, nucleophilic reactions, organic synthesis)

Temperature

15–30 °C; store in dry, ventilated area

Packaging Options

25 L HDPE or glass bottles; bulk 200 L drums

Shelf Life

2 years under recommended storage

Transport & Stacking

Palletized, shrink-wrapped; stack ≤2 drums; follow flammable chemical transport regulations

  1. Triethyl orthoformate
  2. 122-51-0
  3. Triethoxymethane
  4. ETHYL ORTHOFORMATE
  5. diethoxymethoxyethane

Ethyl orthoformate (Triethyl orthoformate) FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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