Search through
Entacapone

Entacapone

CAS Number: 130929-57-6

Molecular Formula: C14H15N3O5

About Entacapone

Entacapone (CAS No: 130929-57-6) functions as a selective, reversible catechol-O-methyltransferase (COMT) inhibitor critical in neurological therapeutics, specifically engineered to prevent the peripheral degradation of levodopa and maintain sustained therapeutic plasma concentrations. The global entacapone API market ...

Synonyms

  • 2-cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide
  • Comtan
  • Comtess
  • entacapone
  • OR 611
View all

Entacapone Specifications

CAS Number
130929-57-6
Molecular Formula
C14H15N3O5
IUPAC Name
(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
PubChem CID
5281081
HSN No
29269000

Pharmaceuticals

An adjunct therapeutic agent used alongside levodopa and carbidopa to treat end-of-dose motor fluctuations in Parkinson's disease patients

Enzyme Inhibition

A selective and reversible catechol-O-methyltransferase inhibitor used to block the peripheral breakdown of dopaminergic precursors

Chemical Research

A biological active compound used as a reference material and building block in neurological and pharmacological studies

Drug Formulation

An active pharmaceutical ingredient utilized in combination solid oral dosage forms to enhance the bioavailability of levodopa

  1. 2-cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide
  2. Comtan
  3. Comtess
  4. entacapone
  5. OR 611

Entacapone FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

Rounded Top

Explore Pharmaceutical Portfolio

Calcium acetate monohydrate

CAS No : 5743-26-0

Calcium acetate monohydrate

Category : Pharmaceutical Actives & Precursors

Sub-Category : Active Pharmaceutical Ingredients (APIs)

Description : Calcium acetate monohydrate (CAS No: 5743-26-0) occupies a critical position in the global specialit...

View Product
Magnesium Sulphate Monohydrate

CAS No : 14168-73-1

Magnesium Sulphate Monohydrate

Category : Pharmaceutical Actives & Precursors, Inorganic Chemicals

Sub-Category : Active Pharmaceutical Ingredients (APIs), Inorganic Salts

Description : We supply high-efficiency magnesium sulphate monohydrate (CAS No: 14168-73-1) archieved across inter...

View Product
P-Nitrobenzoyl Chloride

CAS No : 122-04-3

P-Nitrobenzoyl Chloride

Category : Pharmaceutical Actives & Precursors

Sub-Category : Intermediates & Precursors

Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...

View Product
3-(4 Chloro Phenyl) Glutaric Acid

CAS No : 35271-74-0

Category : Pharmaceutical Actives & Precursors

Sub-Category : Active Pharmaceutical Ingredients (APIs)

Description : 3-(4-Chlorophenyl)glutaric acid (CAS 35271-74-0) is a pivotal building block in the API intermediate...

View Product