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Triisopropyl borate (CAS 5419-55-6) is a vital organoboron reagent and Lewis acid catalyst used extensively by American chemical manufacturers for the synthesis of boronic acids and esters required in Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. The pharmaceutical sector in the United States increasingly relies on this compound for the precision manufacturing of complex bioactive agents and medicinal intermediates, while the polymer industry utilizes it as a high-performance catalyst for specialty coatings, resins, and waxes. Given its high moisture sensitivity, maintaining a purity level of 98% or higher requires rigorous handling and storage under inert atmospheres to ensure optimal yields in fine chemical and agrochemical applications. As a leading Triisopropyl borate supplier in the US market, we provide high-purity materials that meet stringent domestic regulatory standards, supported by comprehensive documentation including CoA and TDS for all grades. Our American-based teams support partners through the entire product lifecycle, offering services from route scouting and process development to scale-up and pilot-to-commercial manufacturing. We also provide expertise in GMP-compliant quality assurance, regulatory compliance, and domestic and global supply chain logistics.
Triisopropyl borate (CAS 5419-55-6) is a vital organoboron reagent and Lewis acid catalyst used extensively by American chemical manufacturers for the synthesis of boronic acids and esters required in Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. The pharmaceutical sector in the United States increasingly relies on this compound for the precision manufacturing of complex bioactive agents and medicinal intermediates, while the polymer industry utilizes it as a high-performance catalyst for specialty coatings, resins, and waxes. Given its high moisture sensitivity, maintaining a purity level of 98% or higher requires rigorous handling and storage under inert atmospheres to ensur...
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Elemental Derivatives
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Boron Derivatives
Organo-Borates & Borate Esters
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Chemical Properties & Specifications
Flam. Liq. 2 (93.5%) & Eye Irrit. 2 (59.7%)
H225 (93.5%): Highly Flammable liquid and vapor
H319 (59.7%): Causes serious eye irritation
P210, P233, P240, P241, P242, P243, P264+P265, P280, P303+P361+P353, P305+P351+P338, P337+P317, P370+P378, P403+P235, and P501
A reagent used in Pd-catalyzed coupling reactions with aryl halides, such as Suzuki reactions
A reagent used for the preparation of boronic acids and esters
A catalyst involved in the ortho-borylation of 1-substituted naphthalenes
A catalyst used for the production of resins, waxes, paints, and varnishes
A cross-linking agent used in polymer production to enhance mechanical properties and thermal stability
An intermediate used in drug formulation processes to improve solubility and bioavailability
A derivatizing agent used in gas chromatography for the detection and analysis of organic compounds
An additive used in the formulation of surface coatings and adhesives to provide enhanced adhesion and durability
An additive used to improve the quality of motor fuels and lubricant oils
Triisopropyl borate, also known as Boric acid triisopropyl ester or Boron isopropoxide, is a versatile organoboron reagent and Lewis acid catalyst used primarily in organic synthesis for Pd-catalyzed coupling reactions like the Suzuki reaction, the preparation of boronic acids and esters, and the production of resins, waxes, paints, and varnishes
This compound is widely utilized in the pharmaceutical, agrochemical, polymer, electronics, and aerospace industries for applications ranging from medicinal chemistry and drug formulation to the manufacture of surface coatings, adhesives, and flame retardants
Triisopropyl borate is a colorless liquid that is insoluble in water but highly soluble in organic solvents, and it is frequently used as a chemical intermediate, reagent, or cross-linking agent in liquid-phase organic synthesis and industrial manufacturing
Standard analytical specifications include CAS number 5419-55-6, high purity (typically ≥98% or ≥99%), density of 0.815 g/mL, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
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