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Triethyl Benzyl Ammonium Chloride (CAS NO : 56-37-1)

Triethylbenzylammonium Chloride (TEBAC) (CAS 56-37-1) is a premier quaternary ammonium salt that functions as a highly efficient Phase Transfer Catalyst (PTC). TEBAC serves as a vital molecular bridge in biphasic reaction systems, enabling the transport of ionic reagents from an aqueous phase into an organic phase where the substrate resides. This capability allows for complex chemical transformations - such as alkylations, nucleophilic substitutions, and dehydrohalogenations - to occur under milder conditions, with higher yields and reduced solvent waste. In the pharmaceutical and agrochemical sectors, BTEAC is an indispensable processing aid for the synthesis of complex active ingredients, while in industrial polymer science, it acts as a curing accelerator and stabiliser. By providing superior catalytic activity and high thermal stability, TEBAC empowers manufacturers to optimise green chemistry protocols and improve overall process throughput. We are a globally established elemental derivatives supplier, along with a broad portfolio of other speciality chemicals worldwide through comprehensive regulatory documentation (CoA), traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.

Triethyl Benzyl Ammonium Chloride
Triethyl Benzyl Ammonium Chloride

Triethylbenzylammonium Chloride (TEBAC) (CAS 56-37-1) is a premier quaternary ammonium salt that functions as a highly efficient Phase Transfer Catalyst (PTC). TEBAC serves as a vital molecular bridge in biphasic reaction systems, enabling the transport of ionic reagents from an aqueous phase into an organic phase where the substrate resides. This capability allows for complex chemical transformations - such as alkylations, nucleophilic substitutions, and dehydrohalogenations - to occur under milder conditions, with higher yields and reduced solvent waste. In the pharmaceutical and agrochemical sectors, BTEAC is an indispensable processing aid for the synthesis of complex active ingredients,...

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Elemental Derivatives

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Category

Nitrogen

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Sub-category

Ammonium Compounds (Quaternary)

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Chemical Properties & Specifications

Applications of Triethyl Benzyl Ammonium Chloride

API Synthesis

Catalyst in the synthesis of diverse drug classes, particularly in the formation of ethers, esters, and nitriles where reactant solubility is a barrier

Phase Transfer Alkylation

Enables N-alkylation and O-alkylation of sensitive pharmaceutical intermediates without the need for expensive, anhydrous solvents

Reaction Optimization

Reduces reaction times and byproduct formation, leading to cleaner API profiles and easier downstream purification

Herbicide & Pesticide Production

Catalyst in the manufacture of pyrethroid insecticides and various systemic herbicides

Environmental Compliance

Facilitates reactions in aqueous media, reducing the reliance on volatile organic compounds (VOCs) and aligning with sustainable agricultural manufacturing

Powder Coatings

Curing agent and accelerator for epoxy-powder coatings and thermosetting resins

Metallurgical Processing

Within the Metallurgy Chemicals framework, it is utilised in specialised extraction processes and as a surface-active agent in plating baths

Have Questions About Triethyl Benzyl Ammonium Chloride?
We've Got Answers.

In a reaction where one reactant is in water and the other is in oil (organic solvent), they normally cannot meet to react. TEBAC acts as a shuttle, "grabbing" the water-soluble ion and carrying it into the organic phase so the reaction can happen.

While theoretically possible in some aqueous-recycle systems, in most industrial batch processes, TEBAC is removed during the washing phase. Its high efficiency at low loading (often 1–5 mol%) makes it cost-effective even for single-use applications.

Moisture doesn't necessarily destroy the molecule, but because TEBAC is sold by weight, moisture absorption (caking) means you are adding less active catalyst than intended, which can slow down your reaction rate.

Yes, TEBA (Triethylbenzylammonium) is often used interchangeably with TEBAC (the chloride salt), though the "C" explicitly denotes the chloride anion.

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