Sorbitan Mono Stearate (E-491)

CAS Number: 1338-41-6

Molecular Formula: C24H46O6

Purity: Summary: Sorbitan Mono Stearate (E-491) is a non-ionic emulsifier and surfactant used to stabilize oil-water mixtures in food, cosmetics, and pharmaceuticals. Often referred to as Span 60, it is produced by esterifying sorbitol with stearic acid. In the food industry, it is primarily used as a dough stabilizer, bloom retardant in chocolate, and a protectant for dry yeast cells. Typical specifications include a Hydrophilic-Lipophilic Balance (HLB) value of 4.7 and a melting point range of 49–65°C.

Common Fatty Acid: Stearic (C18)

About Sorbitan Mono Stearate (E-491)

Sorbitan Mono Stearate (CAS 1338-41-6) is a vital lipophilic emulsifier in the United States API intermediates market, where a Pharma/API purity of 99% is increasingly mandated by domestic CDMOs to ensure the stability of complex drug delivery systems and topical formulations. Span 60 serves as a high purity fine chemi...

Synonyms

Ablunol S-60
Sorbitan monostearate 250g
Span? 60
Sorbitan, monooctadecanoato
Span 60 - 1KG 1kg

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Sorbitan Mono Stearate (E-491) Specifications

CAS Number

1338-41-6

Molecular Formula

C24H46O6

Molecular Weight

430.62 g/mol

IUPAC Name

[(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] octadecanoate

Canonical SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O

InChI Key

HVUMOYIDDBPOLL-XWVZOOPGSA-N

InChI

1S/C24H46O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h20-21,23-26,28H,2-19H2,1H3/t20-,21+,23+,24+/m0/s1

EINECS Number

215-664-9

MDL Number

MFCD00005366

CAS Number

1338-41-6

Molecular Formula

C24H46O6

Molecular Weight

430.62 g/mol

IUPAC Name

[(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] octadecanoate

Canonical SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O

InChI Key

HVUMOYIDDBPOLL-XWVZOOPGSA-N

InChI

1S/C24H46O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h20-21,23-26,28H,2-19H2,1H3/t20-,21+,23+,24+/m0/s1

EINECS Number

215-664-9

MDL Number

MFCD00005366

Molecular Weight

430.62 g/mol

Purity

Summary: Sorbitan Mono Stearate (E-491) is a non-ionic emulsifier and surfactant used to stabilize oil-water mixtures in food, cosmetics, and pharmaceuticals. Often referred to as Span 60, it is produced by esterifying sorbitol with stearic acid. In the food industry, it is primarily used as a dough stabilizer, bloom retardant in chocolate, and a protectant for dry yeast cells. Typical specifications include a Hydrophilic-Lipophilic Balance (HLB) value of 4.7 and a melting point range of 49–65°C.

Melting Point

53-57 °C

Boiling Point

465 °C

Freezing point

50-52°C

pKa

13.63±0.20

Precise Quality

95%

PSA

126 Å²

logP

8.7

Monoisotopic mass

430.32943918 Da

Molar mass

430.62 g/mol

Food Additive

A widely used non-ionic emulsifier, stabilizer, and thickener (E491) employed in baked goods, dairy products, and confectionery to improve texture, maintain moisture, and enhance shelf life

Yeast Processing Aid

A critical surfactant used in the production of active and instant dry yeast to protect cell membranes during drying and facilitate effective rehydration

Pharmaceutical Excipient

A non-ionic surfactant and solubilizer utilized in drug delivery systems, creams, and ointments to enhance the bioavailability of active ingredients and stabilize emulsions

Industrial Dispersant

A versatile agent used in the manufacture of synthetic fibers, metal machining fluids, coatings, and plastics, and as a brightener in the leather industry.