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Pyridine Hydrofluoride (CAS NO : 62778-11-4)

Pyridine Hydrofluoride (CAS 39230-82-3) is a cornerstone of the North American API intermediates market, where its role as a selective fluorinating agent is vital for synthesizing fluorinated pharmaceuticals with a required Pharma/API purity of 99% to meet rigorous FDA standards. Hydrogen fluoride-pyridine serves as a high purity fine chemical for leading US-based CDMOs who are increasingly seeking custom synthesis services to develop specialized drug candidates while navigating global sourcing shifts toward domestic manufacturing. Olah's reagent is also instrumental for general industry applications at 98% purity, particularly within the US agrochemical and polymer sectors, where its unique reactivity profile supports the production of high-performance materials and crop protection agents through a reliable bulk chemical supplier. We are an established Pyridine Hydrofluoride intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Pyridine Hydrofluoride COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

Pyridine Hydrofluoride
Pyridine Hydrofluoride

Pyridine Hydrofluoride (CAS 39230-82-3) is a cornerstone of the North American API intermediates market, where its role as a selective fluorinating agent is vital for synthesizing fluorinated pharmaceuticals with a required Pharma/API purity of 99% to meet rigorous FDA standards. Hydrogen fluoride-pyridine serves as a high purity fine chemical for leading US-based CDMOs who are increasingly seeking custom synthesis services to develop specialized drug candidates while navigating global sourcing shifts toward domestic manufacturing. Olah's reagent is also instrumental for general industry applications at 98% purity, particularly within the US agrochemical and polymer sectors, where its unique...

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Organic Intermediates

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Halogenated Intermediates

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Chemical Properties & Specifications

Applications of Pyridine Hydrofluoride

Fluorinating Reagent

A versatile and powerful nucleophilic fluorinating agent used for the introduction of fluorine atoms into organic molecules, including the preparation of beta-fluoroamines from amino alcohols, the fluorination of acetylenes, and the geminal fluorination of 2,2-diaryl-1,3-dithiolanes

Pharmaceutical Intermediate

A critical building block and reactant employed in the synthesis of various active pharmaceutical ingredients, medicinal compounds, and enzyme inhibitors such as Vaccinia H1-related phosphatase inhibitors

Deprotecting Reagent

A specialized reagent used in peptide chemistry and organic synthesis for the selective removal of silyl ether protecting groups, such as TBDMS, to reveal original alcohol functional groups

Organic Synthesis Building Block

A functionalized reagent used for diverse transformations including halofluorination reactions, the conversion of alcohols to alkyl fluorides, and the synthesis of complex natural product analogues like curacin A

Chemical Catalyst

An acidic catalyst and medium used to regulate reaction pathways in the development of fine chemicals, dyes, fragrances, and fluoropolymer materials.

Have Questions About Pyridine Hydrofluoride?
We've Got Answers.

Pyridine Hydrofluoride, also known as Olah's reagent, is a liquid fluorinating agent used in organic synthesis to introduce fluorine atoms into molecules and to deprotect silyl ethers

This compound is widely used in the pharmaceutical, agrochemical, rubber, dye, and electronics industries for drug development and crop protection

It is soluble in dichloromethane, acetonitrile, ether, THF, toluene, and sulfolane, and is typically used in liquid-phase fluorination or deprotection protocols

Standard specifications include CAS numbers 32001-55-1 or 62778-11-4, high purity (typically 98% or 99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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