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Phosphorus Halide and Oxyhalide series-comprising Phosphorus Trichloride (PCl3), Phosphorus Oxychloride (POCl3), and Phosphorus Pentachloride (PCl5)- represents the foundational "workhorse" reagents for modern chemical synthesis. These compounds are indispensable for functional group transformations, particularly in the conversion of alcohols and carboxylic acids into their corresponding chlorides and esters. PCl3 serves as the primary precursor in the phosphorus value chain, essential for the production of plasticizers and organophosphorus pesticides. POCl3 (Phosphory| Chloride) is universally recognized for its role in the Vilsmeier-Haack reaction, enabling the formylation of electron-rich aromatics. PCls acts as a more aggressive chlorinating agent compared to its trivalent counterpart, frequently utilized for the synthesis of acid chlorides from carboxylic acids and for the conversion of amides to nitriles. High-purity grades of these reagents are critical for CDMO operations to ensure high yields and minimize side-product formation (such as phosphoric acid impurities). Due to their extreme sensitivity to moisture and the release of HCl gas upon hydrolysis, these products are handled under strict inert atmospheres (Nitrogen/Argon). We are the leading phosphorus derivatives supplier worldwide, ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.
Phosphorus Halide and Oxyhalide series-comprising Phosphorus Trichloride (PCl3), Phosphorus Oxychloride (POCl3), and Phosphorus Pentachloride (PCl5)- represents the foundational "workhorse" reagents for modern chemical synthesis. These compounds are indispensable for functional group transformations, particularly in the conversion of alcohols and carboxylic acids into their corresponding chlorides and esters. PCl3 serves as the primary precursor in the phosphorus value chain, essential for the production of plasticizers and organophosphorus pesticides. POCl3 (Phosphory| Chloride) is universally recognized for its role in the Vilsmeier-Haack reaction, enabling the formylation of electron-rich...
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Elemental Derivatives
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Phosphorus
Phosphorus Halides & Oxyhalides
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Chemical Properties & Specifications
Health: 4, Flammability: 0, Reactivity: 2
Health: 4, Flammability: 0, Reactivity: 2
0 No Hazard, 1 Slight Hazard, 2 Moderate Hazard, 3 Serious Hazard, 4 Severe Hazard
Reacts with water yielding HCl and Phosphoric acids.
Raw material for phosphate plasticizers
Synthesis of water treatment chemicals
Intermediate for herbicides and insecticides
Precursor for phosphonic acid derivatives in drug synthesis
Phosphorus Trichloride is widely used as a raw material in the manufacture of organophosphorus pesticides, flame retardants, and plasticizers. It also serves as a precursor for water treatment chemicals and pharmaceutical intermediates.
Phosphorus Trichloride reacts violently with water, releasing toxic gases such as hydrogen chloride and phosphorous acid. It requires strict moisture control, proper ventilation, and the use of personal protective equipment during handling.
Phosphorus Trichloride is used in the synthesis of phosphonates, which act as scale and corrosion inhibitors in water treatment systems, ensuring the efficiency and longevity of industrial water processes.
