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p-Tolyl Magnesium Bromide (CAS NO : 4294-57-9)

p-Tolylmagnesium Bromide (CAS 4294-57-9) is a pivotal Grignard reagent in the United States API intermediates market, where its role in palladium-catalyzed cross-coupling reactions is essential for synthesizing complex biaryl structures with Pharma/API purity of 99%. 4-Methylphenylmagnesium bromide is increasingly utilized by domestic bulk chemical supplier networks to support the rapid growth of US-based CDMOs, focusing on high purity fine chemicals that meet stringent regulatory standards for semi-finished therapeutic formulations. p-Tolyl Magnesium Bromide facilitates critical carbon-carbon bond formations in custom synthesis services, reflecting a strategic shift toward domestic sourcing to ensure supply chain resilience and compliance with American Chemical Society technical benchmarks for General Industry purity of 98%. We are an established p-Tolyl Magnesium Bromide intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting p-Tolyl Magnesium Bromide COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

p-Tolyl Magnesium Bromide
p-Tolyl Magnesium Bromide

p-Tolylmagnesium Bromide (CAS 4294-57-9) is a pivotal Grignard reagent in the United States API intermediates market, where its role in palladium-catalyzed cross-coupling reactions is essential for synthesizing complex biaryl structures with Pharma/API purity of 99%. 4-Methylphenylmagnesium bromide is increasingly utilized by domestic bulk chemical supplier networks to support the rapid growth of US-based CDMOs, focusing on high purity fine chemicals that meet stringent regulatory standards for semi-finished therapeutic formulations. p-Tolyl Magnesium Bromide facilitates critical carbon-carbon bond formations in custom synthesis services, reflecting a strategic shift toward domestic sourcing...

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Metallurgy Chemicals

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Metal Compounds & Salts

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Specialty Organometallic Compounds

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Chemical Properties & Specifications

Applications of p-Tolyl Magnesium Bromide

Grignard Reagent

A common organometallic reagent used as a nucleophile in organic synthesis to form new carbon-carbon bonds, typically by reacting with carbonyl compounds to produce secondary or tertiary alcohols

Cross-coupling Reagent

A versatile building block employed in various palladium, nickel, or iron-catalyzed cross-coupling reactions, such as the Kumada reaction, to synthesize biaryl compounds and complex organic molecules

Polymerization Catalyst

A functional reagent used as a catalyst in cationic polymerization reactions to initiate the formation of high-molecular-weight polymers

Synthetic Intermediate

A reactive intermediate used to remove functional groups like chlorine, fluorine, sulfides, and tosylates from organic molecules in specialized chemical transformations.

Have Questions About p-Tolyl Magnesium Bromide?
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p-Tolyl Magnesium Bromide is an organomagnesium compound and a common Grignard reagent used in organic synthesis for the formation of carbon-carbon bonds and the introduction of the tolyl group into molecules

This compound is widely used in the pharmaceutical and agrochemical industries for the synthesis of complex organic molecules, medicines, and pesticides

It is typically supplied as a solution in anhydrous solvents such as tetrahydrofuran (THF) or diethyl ether and is compatible with liquid-phase organic synthesis under inert conditions

Standard specifications include CAS number 4294-57-9, molecular weight 195.34, purity levels (typically 99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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