Hydantoin (CAS 461-72-3), also known as glycolylurea, serves as a vital heterocyclic building block in the pharmaceutical industry with a 99% purity standard for the synthesis of anticonvulsants like phenytoin and nitrofurantoin, especially as U.S. based CDMOs increasingly require high purity fine chemicals to meet str...
Hydantoin Specifications
CAS Number
461-72-3
Molecular Formula
C3H4N2O2
Molecular Weight
100.08 g/mol
IUPAC Name
imidazolidine-2,4-dione
Canonical SMILES
C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
InChI Key
WJRBRSLFGCUECM-UHFFFAOYSA-N
PubChem CID
10006
CAS Number
461-72-3
Molecular Formula
C3H4N2O2
Molecular Weight
100.08 g/mol
IUPAC Name
imidazolidine-2,4-dione
Canonical SMILES
C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
InChI Key
WJRBRSLFGCUECM-UHFFFAOYSA-N
PubChem CID
10006
Molecular Weight
100.08 g/mol
Physical appearance
White to yellow powder to crystal
Pharmaceutical Intermediate
A privileged heterocyclic scaffold and critical building block used in the synthesis of anticonvulsants, such as phenytoin and fosphenytoin, as well as various muscle relaxants, antidiabetics, and anticancer agents
Organic Synthesis Building Block
A versatile reactant used in the synthesis of amino acids, N-benzyl aplysinopsin analogs, and heterocyclic derivatives for drug discovery
Biocide and Disinfectant
A precursor for N-halogenated derivatives used as antimicrobial agents and sanitizers in water treatment and industrial cooling systems
Polymer Additive
A functional additive employed to enhance the thermal stability, durability, and resistance to degradation of plastics and resins
Cosmetic Preservative
A precursor for antimicrobial agents like DMDM hydantoin, which release trace amounts of formaldehyde to prevent microbial growth and extend the shelf life of personal care products
Chemical Auxiliary
A silver complexing agent utilized in cyanide-free electroplating processes for the electronics manufacturing industry and an aggregation suppressor for protein refolding in bioprocessing.