

High-purity Hippuric Acid (CAS 495-69-2) is widely used in the United States as a biomarker, analytical reagent, and synthetic intermediate. Hippuric acid, also referred to as hippurate or Hippursäure, is a naturally occurring benzoylated amino acid found in mammalian urine and is commonly supplied by specialty chemical providers for research and analytical applications. It serves as a key conjugation metabolite of benzoic acid and is employed as a biomarker for toluene exposure and dietary phenolic metabolism. This analytical-grade chemical is primarily used in biochemical assays, metabolism and toxicology studies, and controlled organic synthesis. Hippuric Acid is a water-soluble, stable crystalline material, making it well-suited for laboratory, research, and clinical applications. Scimplify supplies Hippuric Acid for the U.S. market with consistent quality, defined specifications, and dependable supply continuity, supporting laboratories, research institutions, and specialty chemical users across the United States with reliable lead times.


High-purity Hippuric Acid (CAS 495-69-2) is widely used in the United States as a biomarker, analytical reagent, and synthetic intermediate. Hippuric acid, also referred to as hippurate or Hippursäure, is a naturally occurring benzoylated amino acid found in mammalian urine and is commonly supplied by specialty chemical providers for research and analytical applications. It serves as a key conjugation metabolite of benzoic acid and is employed as a biomarker for toluene exposure and dietary phenolic metabolism. This analytical-grade chemical is primarily used in biochemical assays, metabolism and toxicology studies, and controlled organic synthesis. Hippuric Acid is a water-soluble, stable c...
Elemental Derivatives
Miscellaneous Functional Intermediates
General Functional Reagents
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Chemical Properties & Specifications
Acute Oral Toxicity Category 4 Skin Irritation Category 2 Eye Damage Category 1 STOT-SE Category 3 (respiratory irritation)
Warning
GHS07, GHS05
Not controlled or restricted under major chemical directives
Used in laboratories for metabolic profiling, enzymatic assays, and as a precursor in the synthesis of benzamide derivatives and fluorescent dyes
*Naturally Derived Biomarker: Validates metabolic pathways. *Stable Crystalline Form: Melts at ~187–191 °C *High Purity (>98%): Suitable for research-grade use
Store at ≤30 °C in a dry, ventilated place
Stable ≥24 months under recommended conditions
Available in HDPE bottles or aluminum-lined paper bags (5 g–1 kg)
Keep tightly sealed to avoid moisture uptake
It is a principal glycine conjugate of benzoic acid, used to assess liver function and to evaluate toluene exposure.
Available in 98–99% purity as standard, suitable for analytical and assay work.
Dissolve in buffer or organic solvent at known concentrations; commonly used in enzyme kinetics and metabolic profiling.
Handle with gloves and goggles. Avoid inhaling dust or mist. Use in well-ventilated settings.
HPLC, LC–MS, GC–MS (as derivatized ester), and colorimetric assays involving benzene sulfonyl chloride.