

Ethylal (CAS 462-95-3), also known as diethoxymethane, has gained significant traction in the United States as a high purity fine chemicals solvent, particularly in the API intermediates market where its ability to replace more toxic ethers like THF or DCM aligns with the green chemistry initiatives favored by the American Chemical Society. Diethyl formal (462-95-3) is increasingly utilized by domestic CDMOs for custom synthesis services, as it offers superior stability and lower volatility for specialized pharmaceutical reactions requiring General Industry purity of 98% or higher to ensure regulatory compliance. Formaldehyde diethyl acetal has become a critical reagent for US-based bulk chemical suppliers catering to the aerospace and electronics sectors, where a shift toward domestic sourcing and high-performance, low-impurity solvents is essential for maintaining supply chain resilience and technical precision. As an established Ethylal suppliers in the united states, we ensure dependable supply, consistent quality, and complete regulatory documentation, including CoA and TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination


Ethylal (CAS 462-95-3), also known as diethoxymethane, has gained significant traction in the United States as a high purity fine chemicals solvent, particularly in the API intermediates market where its ability to replace more toxic ethers like THF or DCM aligns with the green chemistry initiatives favored by the American Chemical Society. Diethyl formal (462-95-3) is increasingly utilized by domestic CDMOs for custom synthesis services, as it offers superior stability and lower volatility for specialized pharmaceutical reactions requiring General Industry purity of 98% or higher to ensure regulatory compliance. Formaldehyde diethyl acetal has become a critical reagent for US-based bulk che...
Industrial Chemicals
Solvents & Carriers
Ethers & Ether-Based Solvents
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Chemical Properties & Specifications
P210, P233, P240, P241, P242, P243, P261, P264, P280, P303+P361+P353, P305+P351+P338, P332+P313, P337+P313, P362, P370+P378, P403+P235, and P501
Flam. Liq. 2 (100%)
Skin Irrit. 2 (100%)
A versatile and high-purity solvent, also known as diethoxymethane, utilized in various industrial and professional applications for dispersing organic and inorganic pigments and fillers in aqueous and solvent-based systems
A critical organic building block employed in the manufacturing of other substances and the formulation of chemical preparations
A functional additive used in aqueous industrial, wood, decorative, and printing ink formulations to improve pigment wetting, enhance rheological stability, and provide lower viscosity with higher gloss
A high-performance component used in the formulation of specialized cleaning agents, thinners, and paint removers
A high-purity chemical used for synthesis and academic research as a sustainable, greener alternative solvent.
Ethylal, also known as diethoxymethane, is a versatile acetal solvent and chemical intermediate used in organic synthesis, particularly as a substitute for dichloromethane and toluene in O-alkylation reactions
It is widely utilized in the pharmaceutical, fragrance, and chemical manufacturing industries for synthesis, as a specialized solvent, and in the production of coatings, paints, and adhesives
Ethylal is compatible with liquid-phase protocols, acting as an excellent solvent for organolithium compounds and a surface tension reducer in various resin systems
Standard specifications include CAS number 462-95-3, purity (typically ≥99%), density, and boiling point, with documentation such as COA, TDS, impurity reports, and regulatory compliance documents available
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
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