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Berberine chloride

Berberine chloride

CAS Number: 633-65-8

Molecular Formula: C20H18NO4.Cl / C20H18ClNO4

Strength: Berberine 97%, ME & NGLP: 25%Berberis aristata Extract & Coptis ExtractAlkaloids/Metabolic Actives & AMPK ActivatorsBlood Glucose Support & Cardiovascular Health AdditivesPCOS Support & Lipid Management Actives

About Berberine chloride

Berberine is a bioactive quaternary ammonium salt belonging to the protoberberine group of benzylisoquinoline alkaloids. Typically sourced from Berberis aristata (Indian Barberry) - most powerful natural compounds for activating the AMPK pathway (the body's "metabolic master switch"). Typically offered as Berberine HCL...

Berberine chloride Specifications

CAS Number
633-65-8
Molecular Formula
C20H18NO4.Cl / C20H18ClNO4
Molecular Weight
371.814 (Standard specification)
IUPAC Name
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene chloride
Canonical SMILES
COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
InChI Key
VKJGBAJNNALVAV-UHFFFAOYSA-M
HSN No
3003409000
Molecular Weight
371.814 (Standard specification)
PSA
40.800 (Standard specification)
LogP
0.10030 (Standard specification)
Physical State
yellow crystalline powder (varies on grades)
Density
1.654g/cm3 (Standard specification)
Melting Point
200ºC (Standard specification)
Assay
Berberine 97%
Plant Source
Berberis aristata (Bark/Root)
Product Form
Micro-encapsulated (ME & NGLP) Powder
Strength
ME & NGLP: 25%
Solvents
Meets US/EU/Japan quality and residual solvent requirements

Metabolic Health & Glucose Management

Extensive supplements targeting insulin sensitivity, blood glucose management. To Manage Type 2 diabetes and hyperlipidaemia. Efficacy in lowering blood glucose and HbA1c is often compared to metformin

Cardiovascular Support

Maintains healthy cholesterol and triglyceride levels. Formulations targeting healthy cholesterol levels (LDL reduction) and overall heart health

Microbial Balance

Broad-spectrum antimicrobial activity, supporting gut health and immunity and overall metabolism, Effective against (e.g., S.mutans, E. coll), fungi (Trichophyton), and parasites

Anti-inflammatory

Reduction of pro-inflammatory mediators like TNF-a and NF-KB

PCOS & Weight Management

Core ingredient in hormonal balance supplements and metabolic-boosting formulations

Gastrointestinal Health

Antimicrobial properties to support a healthy gut microbiome and address SIBO (Small Intestinal Bacterial Overgrowth)

Pharmaceutical Manufacturing

High tableting recovery (95–98%), ensuring the active salt remains stable during high-pressure industrial processing

Berberine chloride FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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