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Azide-PEG3-Amine

Azide-PEG3-Amine

CAS Number: 134179-38-7

Molecular Formula: C8H18N4O3

About Azide-PEG3-Amine

Azido-PEG3-amine (CAS 134179-38-7) serves as a critical heterobifunctional crosslinker in the burgeoning bioconjugation sector, where its primary amine and azide groups facilitate site-specific labeling and the construction of complex antibody-drug conjugates (ADCs) via high-efficiency click chemistry. 11-Azido-3,6,9-t...

Azide-PEG3-Amine Specifications

CAS Number

134179-38-7

Molecular Formula

C8H18N4O3

Molecular Weight

218.25 g/mol

IUPAC Name

1-Amino-8-azido-3,6-dioxaoctane

Canonical SMILES

C(COCCOCCN=[N+]=[N-])N

InChI Key

FPVCVHVTMPCZTH-UHFFFAOYSA-N

PubChem CID

2735280

CAS Number

134179-38-7

Molecular Formula

C8H18N4O3

Molecular Weight

218.25 g/mol

IUPAC Name

1-Amino-8-azido-3,6-dioxaoctane

Canonical SMILES

C(COCCOCCN=[N+]=[N-])N

InChI Key

FPVCVHVTMPCZTH-UHFFFAOYSA-N

PubChem CID

2735280

Molecular Weight

218.25 g/mol

Physical appearance

Colorless to yellow clear liquid

Bioconjugation Reagent

A bifunctional PEG linker containing a terminal primary amine and an azide group used to link biomolecules such as proteins, peptides, or nucleic acids through stable amide bond formation and click chemistry

PROTAC Linker

A critical heterobifunctional building block utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs) to connect an E3 ubiquitin ligase ligand to a target protein ligand for selective protein degradation

ADC Linker

A non-cleavable triethylene glycol spacer employed in the development of antibody-drug conjugates (ADCs) to attach cytotoxic payloads to antibodies

Surface Functionalization Agent

A hydrophilic crosslinker used to modify surfaces with reactive groups for the development of biosensors, bioassays, and drug delivery systems.

Azide-PEG3-Amine FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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