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3-Bromo-8-methylimidazo[1,2-a] pyridine-6-carboxylic acid

3-Bromo-8-methylimidazo[1,2-a] pyridine-6-carboxylic acid

CAS Number: 2167072-16-2

Purity: Purity 99.90%

About 3-Bromo-8-methylimidazo[1,2-a] pyridine-6-carboxylic acid

3-Bromo-8-methylimidazo[1,2-a]pyridine-6-carboxylic acid (C₉H₇BrN₂O₂) is a highly functionalised, bicyclic heterocyclic building block extensively utilised as an advanced intermediate in discovery-phase medicinal chemistry, high-throughput screening campaigns, and commercial API synthesis. Due to its rigid, electron-ri...

3-Bromo-8-methylimidazo[1,2-a] pyridine-6-carboxylic acid Specifications

CAS Number
2167072-16-2
Molecular Weight
255.07
IUPAC Name
3-bromo-8-methylimidazo[1,2-a]pyridine-6-carboxylic acid
Canonical SMILES
CC1=C2N=C(C(=N2C=C1C(=O)O)Br)H
InChI Key
JZHAXJVYJZDREO-UHFFFAOYSA-N
InChI
InChI=1S/C9H7BrN2O2/c1-5-2-6(9(13)14)3-12-7(10)4-11-8(5)12/h2-4H,1H3,(H,13,14)
Molecular Weight
255.07
Density (Predicted)
1.794±0.14 g/cm3 Temp: 25 °C; Press: 760 Torr
pKa (Predicted)
0.325±0.41 Most Acidic Temp: 25 °C
Chromatographic purity by HPLC (%)
Purity 99.90%

Primary Application

High-throughput medicinal chemistry screening, library synthesis, and clinical trial R&D Commercial-scale active pharmaceutical ingredient (API) synthesis and regulated scale-up campaigns.

Targeted Small-Molecule Kinase Inhibitors

Foundational core structural pharmacophore for synthesising selective tyrosine kinase inhibitors (TKIs) and mitogen-activated protein kinase (MAPK) pathway modulators

Next-Generation Antimicrobial & Antiviral R&D

Key scaffold in constructing functionalised nitrogen-bridgehead systems engineered to combat multi-drug-resistant (MDR) bacterial strains and viral replication assemblies

Oncology Drug Discovery Portfolios

Integrated by global biotechnology entities into DNA-damage response (DDR) inhibitor designs and enzyme-targeted cell signaling inhibitors

Supramolecular & Divergent Synthesis Toolkits

Highly reactive, bifunctional connector matrix for building sophisticated macrocycles and specialised biochemical screening probes

3-Bromo-8-methylimidazo[1,2-a] pyridine-6-carboxylic acid FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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