"DTT (DL-1,4-Dithiothreitol) is a small-molecule reducing agent widely used in biochemistry and molecular biology. It functions by reducing disulfide bonds in proteins and peptides, helping maintain enzyme activity and protein stability by preventing oxidation. It is an enantiomer of a L-1,4-dithiothreitol. A reagent commonly used in biochemical studies for reducing disulphides to dithiols."
"DTT (DL-1,4-Dithiothreitol) is a small-molecule reducing agent widely used in biochemistry and molecular biology. It functions by reducing disulfide bonds in proteins and peptides, helping maintain enzyme activity and protein stability by preventing oxidation. It is an enantiomer of a L-1,4-dithiothreitol. A reagent commonly used in biochemical studies for reducing disulphides to dithiols."
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Acute Toxicity (Oral): Category 4 Skin Irritation: Category 2 Eye Irritation: Category 2A Hazardous to the Aquatic Environment (Chronic): Category 3
H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H412: Harmful to aquatic life with long-lasting effects.
P280: Wear protective gloves and eye protection. P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P302+P352: IF ON SKIN: Wash with plenty of water. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. P273: Avoid release to the environment.
Used as a reducing agent to maintain protein stability.
Prevents incorrect disulfide bond formation in proteins, aiding in protein folding studies.
Protects enzymatic activity by maintaining thiol groups in their reduced state.
Used in electrophoresis to prevent nucleic acid oxidation.
Store at room temperature (typically 15–30°C or 59–86°F).
Keep in a dry, inert atmosphere. Avoid exposure to air, moisture, and oxidizing agents.
Store in original, tightly sealed containers under nitrogen or argon gas to prevent oxidation.
Available in 1 g, 5 g, 10 g, and bulk quantities. Custom packaging available upon request.
