Dorzolamide Hydrochloride

CAS Number: 130693-82-2

Molecular Formula: C10H17ClN2O4S3

About Dorzolamide Hydrochloride

The global ophthalmic sector is currently witnessing a transformative shift in the management of intraocular pressure, with Dorzolamide Hydrochloride (CAS No: 130693-82-2) positioned as a fundamental carbonic anhydrase inhibitor for treating open-angle glaucoma and ocular hypertension. Market intelligence indicates a s...

Synonyms

4-ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide
5,6-dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
dorzolamide
Dorzolamide Chibret
dorzolamide hydrochloride

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Dorzolamide Hydrochloride Specifications

CAS Number

130693-82-2

Molecular Formula

C10H17ClN2O4S3

IUPAC Name

(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride

Canonical SMILES

CCNC1CC(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl

InChI Key

OSRUSFPMRGDLAG-QMGYSKNISA-N

InChI

InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1

HSN No

30049099

CAS Number

130693-82-2

Molecular Formula

C10H17ClN2O4S3

IUPAC Name

(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride

Canonical SMILES

CCNC1CC(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl

InChI Key

OSRUSFPMRGDLAG-QMGYSKNISA-N

InChI

InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1

HSN No

30049099

Precautionary Statement Codes

P260, P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P314, P330, and P501

Hazard Classes and Categories

Acute Tox. 4 Skin Irrit. 2

Pharmaceutical Active Ingredient

A topical carbonic anhydrase inhibitor used in ophthalmic solutions to treat elevated intraocular pressure associated with open-angle glaucoma and ocular hypertension

Carbonic Anhydrase Inhibitor

A highly specific inhibitor of carbonic anhydrase II that reduces the production of aqueous humor to preserve optic nerve health and prevent vision loss

Research Tool

A biochemical agent utilized in clinical and pharmacological studies to investigate the role of isoenzyme-specific inhibition in ocular fluid dynamics.

4-ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide
5,6-dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
dorzolamide
Dorzolamide Chibret
dorzolamide hydrochloride