Dimethyl Fumarate

CAS Number: 624-49-7

Molecular Formula: C6H8O4

About Dimethyl Fumarate

Dimethyl Fumarate CAS 624-49-7 serves as a premier Nrf2 activator within the API intermediates market, primarily utilised for the synthesis of advanced therapeutics targeting relapsing multiple sclerosis and moderate-to-severe plaque psoriasis. Fumaric acid dimethyl ester is increasingly sought after by CDMO partners p...

Dimethyl Fumarate Specifications

CAS Number

624-49-7

Molecular Formula

C6H8O4

Molecular Weight

144.13 g/mol

IUPAC Name

dimethyl (2E)-but-2-enedioate

Canonical SMILES

COC(=O)C[C@@H](C(=O)OC)S

InChI Key

LDCRTTXIJACKKU-ONEGZZNKSA-N

CAS Number

624-49-7

Molecular Formula

C6H8O4

Molecular Weight

144.13 g/mol

IUPAC Name

dimethyl (2E)-but-2-enedioate

Canonical SMILES

COC(=O)C[C@@H](C(=O)OC)S

InChI Key

LDCRTTXIJACKKU-ONEGZZNKSA-N

Molecular Weight

144.13 g/mol

Physical appearance

White to almost white powder to crystal

Pharmaceutical Intermediate

An oral therapeutic agent and potent immunomodulator used in the formulation of prescription medications for the treatment of relapsing forms of multiple sclerosis (MS) and chronic plaque psoriasis

Organic Synthesis Building Block

A versatile methyl ester of fumaric acid utilized as a ligand in the synthesis of Ni(II)-based catalytic systems for Negishi alkylations and as a precursor for various chemical compounds and polymers

Industrial Biocide

A chemical additive historically employed in the preservation of leather, furniture, and consumer goods to inhibit mold growth during storage and transport

Research Tool

A certified reference material and Nrf2 activator used in academic and clinical studies to investigate anti-inflammatory and antioxidant responses in neurodegenerative and autoimmune disease models.