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Diethyl (tosyloxy)methylphosphonate (CAS 31618-90-3) is a critical phosphonate building block in the API intermediates market, primarily utilized for the synthesis of antiviral nucleotide analogs such as Tenofovir and Adefovir. As a specialized bulk chemical supplier, we see a significant trend where global pharmaceutical manufacturers are shifting toward audited supply chains to ensure high-purity fine chemicals (Pharma/API purity 99%) that meet stringent genotoxic impurity limits. Diethoxyphosphorylmethyl p-toluenesulfonate (CAS 31618-90-3) serves as an essential alkylating agent for the introduction of the phosphonomethyl moiety in complex drug synthesis. The rise of CDMO growth has accelerated the demand for custom synthesis services capable of delivering this intermediate with precise analytical validation, ensuring that final drug substances maintain high quality and regulatory compliance (Pharma/API purity 99%). Diethyl p-toluenesulfonyloxymethylphosphonate (CAS 31618-90-3) is increasingly sought for its high reactivity in Horner-Wadsworth-Emmons olefination and as a precursor for various pharmaceutical and specialty chemical applications. Current market dynamics favor suppliers who provide robust regulatory documentation and transparent sourcing to mitigate risks associated with global supply chain disruptions, reinforcing the necessity for reliable partners in the high-purity chemicals sector (Pharma/API purity 99% | General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API. We offer a broad range of pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical support (HPLC/NMR/MS), Diethyl p-toluenesulfonyloxymethylphosphonate (DESMP) COA/TDS/SDS, region-specific regulatory support, reliable lead times, and worldwide supply chain capabilities.
Diethyl (tosyloxy)methylphosphonate (CAS 31618-90-3) is a critical phosphonate building block in the API intermediates market, primarily utilized for the synthesis of antiviral nucleotide analogs such as Tenofovir and Adefovir. As a specialized bulk chemical supplier, we see a significant trend where global pharmaceutical manufacturers are shifting toward audited supply chains to ensure high-purity fine chemicals (Pharma/API purity 99%) that meet stringent genotoxic impurity limits. Diethoxyphosphorylmethyl p-toluenesulfonate (CAS 31618-90-3) serves as an essential alkylating agent for the introduction of the phosphonomethyl moiety in complex drug synthesis. The rise of CDMO growth has accel...
Chemical Properties & Specifications
P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, and P362
Skin Irrit. 2 (100%)
Eye Irrit. 2 (100%)
Diethyl p-toluene sulfonyl oxymethyl phosphonate (DESMP) is primarily utilized as a critical intermediate in the synthesis of anti-retroviral and nucleoside antiviral drugs, specifically for the production of Tenofovir and Adefovir used in the treatment of HIV, Hepatitis B (HBV), and Cytomegalovirus (CMV)
The compound serves as a valuable phosphorylating agent and building block in the development of phosphine ligands, herbicides, and fungicides within the agrochemical and fine chemical industries
It is employed in laboratory research and development for the synthesis of acyclic nucleoside phosphonates and other bioactive molecules to investigate viral replication inhibition.
Diethyl p-toluene sulfonyl oxymethyl phosphonate, commonly known as DESMP, is a synthetic intermediate and phosphorylating agent primarily used in the synthesis of nucleoside antiviral drugs like Tenofovir and Adefovir, as well as in the production of herbicides and fungicides
This chemical is widely utilized in the pharmaceutical, agrochemical, and biotechnology industries for drug development and pesticide manufacturing
It is compatible with various organic solvents such as dichloromethane, ethyl acetate, and methanol, and is typically used in liquid-phase chemical synthesis
Standard specifications include CAS number 31618-90-3, high purity (typically ≥97% or ≥98.5%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and mode of transport.
