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Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate (CAS NO : 42771-81-3)

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate (CAS 42771-81-3) is a critical precursor in the API intermediates market, primarily utilized for the synthesis of Flurbiprofen and related non-steroidal anti-inflammatory drugs where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure precise medicinal chemistry outcomes. Diethyl 2-(2-fluoro-[1,1-biphenyl]-4-yl)-2-methylmalonate serves as a high-performance building block in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent international pharmacopeia standards. Propanedioic acid, 2-(2-fluoro[1,1-biphenyl]-4-yl)-2-methyl-, 1,3-diethyl ester remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing while maintaining precise crystalline morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an globally established Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate (CAS 42771-81-3) is a critical precursor in the API intermediates market, primarily utilized for the synthesis of Flurbiprofen and related non-steroidal anti-inflammatory drugs where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure precise medicinal chemistry outcomes. Diethyl 2-(2-fluoro-[1,1-biphenyl]-4-yl)-2-methylmalonate serves as a high-performance building block in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent international pharmacopeia...

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Chemical Properties & Specifications

Applications of Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate

Pharmaceutical Intermediate

An important building block utilized in the synthesis of the nonsteroidal anti-inflammatory drug (NSAID) flurbiprofen

Analytical Reference Standard

A fully characterized chemical compound used for analytical method development, method validation (AMV), and quality control (QC) applications to ensure the quality and traceability of flurbiprofen according to pharmacopeial standards

Organic Synthesis Building Block

A functionalized malonate derivative used in academic and industrial research for the development of complex molecules and medicinal compounds.

Have Questions About Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate?
We've Got Answers.

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate, also known by CAS 42771-81-3, is a fully characterized chemical compound used as a reference standard for the API Flurbiprofen. It is utilized for analytical method development, validation, and quality control applications during the synthesis and formulation stages of drug development

This compound is primarily used in the pharmaceutical and analytical research industries as a reference standard and impurity for quality control in the production of nonsteroidal anti-inflammatory drugs

It is soluble in chloroform and methanol and is typically handled as a syrup or liquid for use in analytical laboratory settings

Standard specifications include CAS number 42771-81-3, molecular formula C20H21FO4, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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