Bedaquiline Fumarate

CAS Number: 845533-86-0

Molecular Formula: C36H35BrN2O6

Purity: Bedaquiline Fumarate 98% purity

About Bedaquiline Fumarate

Bedaquiline Fumarate (CAS 1051475-10-3) represents a critical advancement in the API intermediates market, specifically as a diarylquinoline antimycobacterial indicated for the treatment of multi-drug resistant tuberculosis. R207910 fumarate salt has seen significant demand growth within the high purity fine chemicals ...

Synonyms

(1R,2S)-1-(6-bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-(3-fluorophenyl)-1-phenyl-butan-2-ol
AIDS-222089
AIDS222088
Bedaquiline
bedaquiline fumarate

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Bedaquiline Fumarate Specifications

CAS Number

845533-86-0

Molecular Formula

C36H35BrN2O6

Molecular Weight

671.6 g/mol

IUPAC Name

(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol;(E)-but-2-enedioic acid

Canonical SMILES

CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(=O)O)C(=O)O

InChI Key

ZLVSPMRFRHMMOY-WWCCMVHESA-N

InChI

InChI=1S/C32H31BrN2O2.C4H4O4/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3;5-3(6)1-2-4(7)8/h4-17,20-21,30,36H,18-19H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t30-,32-;/m1./s1

HSN No

29420090

CAS Number

845533-86-0

Molecular Formula

C36H35BrN2O6

Molecular Weight

671.6 g/mol

IUPAC Name

(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol;(E)-but-2-enedioic acid

Canonical SMILES

CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(=O)O)C(=O)O

InChI Key

ZLVSPMRFRHMMOY-WWCCMVHESA-N

InChI

HSN No

29420090

Molecular Weight

671.6 g/mol

Purity

Bedaquiline Fumarate 98% purity

Antitubercular Agent

A diarylquinoline antibiotic specifically used in combination therapy for the treatment of pulmonary multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) by inhibiting mycobacterial ATP synthase

ATP Synthase Inhibitor

A potent antimycobacterial agent that blocks the proton pump of adenosine 5-triphosphate (ATP) synthase to disrupt energy metabolism in Mycobacterium tuberculosis

Research Tool

A biological small molecule utilized in scientific research for bioluminescence imaging, protein-protein interaction studies, and disease modeling involving both tuberculous and non-tuberculous mycobacteria.

(1R,2S)-1-(6-bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-(3-fluorophenyl)-1-phenyl-butan-2-ol
AIDS-222089
AIDS222088
Bedaquiline
bedaquiline fumarate