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8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione (CAS 666816-98-4) is a critical xanthine-based scaffold in the API intermediates market, primarily utilized for the synthesis of DPP-4 inhibitors like Linagliptin, where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure precise molecular docking and therapeutic efficacy. 8-Bromo-7-(2-butynyl)-3-methylxanthine serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory and environmental standards. 8-Bromo-3-methyl-7-(but-2-ynyl)-1H-purine-2,6(3H,7H)-dione remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing while maintaining precise crystalline morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an globally established 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione (CAS 666816-98-4) is a critical xanthine-based scaffold in the API intermediates market, primarily utilized for the synthesis of DPP-4 inhibitors like Linagliptin, where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure precise molecular docking and therapeutic efficacy. 8-Bromo-7-(2-butynyl)-3-methylxanthine serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory and environmental standard...
Chemical Properties & Specifications
P261, P305, P338, and P351
Skin Sens. 1 (96.4%)
Eye Irrit. 2A (100%)
A critical organic building block and precursor primarily used in the multi-step synthesis of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin for the management of type 2 diabetes
A functionalized xanthine derivative employed in medicinal chemistry research and industrial manufacturing to develop complex heterocyclic molecules with diverse biological activities
A high-purity standard used in analytical laboratories for quality control, impurity profiling, and structural elucidation during the production of bulk drug substances.
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a heterocyclic building block and pharmaceutical intermediate primarily used in the synthesis of Linagliptin, a medication for type 2 diabetes
This compound is widely used in the pharmaceutical industry for drug discovery, research, and the production of active pharmaceutical ingredients
It is slightly soluble in DMSO and methanol and is typically handled as a solid powder or crystal for organic synthesis and laboratory research
Standard specifications include CAS number 666816-98-4, high purity (typically >=98% or >=99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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