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7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant) (CAS NO : 39713-40-1)

A key fused-ring heterocyclic compound, this intermediate is used in the synthesis of advanced CNS-targeting molecules and diversified heterocyclic scaffolds. Its dione structure enables downstream reactivity in pharmaceutical, agrochemical, and custom synthesis workflows.

7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant)
7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant)

A key fused-ring heterocyclic compound, this intermediate is used in the synthesis of advanced CNS-targeting molecules and diversified heterocyclic scaffolds. Its dione structure enables downstream reactivity in pharmaceutical, agrochemical, and custom synthesis workflows.

Industries 1Industries

Industry

Pharmaceutical

Category 1Category

Category

Pharmaceutical Actives & Precursors

Sub-categorySub-category 1

Sub-category

Intermediates & Precursors

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Chemical Properties & Specifications

Applications of 7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant)

CNS Drug Synthesis

Serves as a key intermediate for neuroactive tricyclic frameworks.

Agrochemical Scaffolding

Utilized in fine-tuning of insecticides and herbicide backbones.

Custom Heterocyclic Libraries

Applied in medicinal chemistry programs requiring fused aromatic pyridines.

Analytical & SAR Studies

Used in structure-activity relationship mapping for ring-closed derivatives.

Have Questions About 7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant)?
We've Got Answers.

It’s a core intermediate in CNS, oncology, and anti-inflammatory drug scaffolds, primarily used for structure-building in tricyclic frameworks.

5H,6H,7H,8H,9H-cyclohepta[b]pyridine-5,9-dione

5,9(6H)-Dione, 7,8-dihydro-5H-cyclohepta[b]pyridine and Heterocyclic intermediate with fused pyridine scaffold

It is typically supplied as a non-GMP intermediate for use in early-stage or pilot pharmaceutical programs.

COA, MSDS, and if required, elemental analysis or NMR spectrum can be provided.

Soluble in DMF, DMSO, and moderately in methanol or ethanol; minimal solubility in water.

Yes, with lead time of 2–4 weeks, quantities can range from 10 g lab scale to multi-kg under CRAMS/CDMO engagements.

Typically ≥ 98% by HPLC

COA and MSDS standard; further docs available on request

100% advance for lab quantities; negotiable for scale-up batches

Yes, with proper non-GMP classification and shipment docs

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