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A key fused-ring heterocyclic compound, this intermediate is used in the synthesis of advanced CNS-targeting molecules and diversified heterocyclic scaffolds. Its dione structure enables downstream reactivity in pharmaceutical, agrochemical, and custom synthesis workflows.
![7,8-DIHYDRO-5H-CYCLOHEPTA[b]PYRIDINE-5,9(6H)-DIONE (Rimegepant)](/_next/image?url=https%3A%2F%2Fcdn.scimplify.com%2Fproducts%2Fimages%2F6800e9ab13120a5667f0c6ca%2F122e542d-fa5b-4525-9b1d-7b938b65ec7b.png&w=3840&q=75)
A key fused-ring heterocyclic compound, this intermediate is used in the synthesis of advanced CNS-targeting molecules and diversified heterocyclic scaffolds. Its dione structure enables downstream reactivity in pharmaceutical, agrochemical, and custom synthesis workflows.
Chemical Properties & Specifications
Not classified under standard hazard classes
For R&D or intermediate use only; not for direct therapeutic use
P280: Wear protective gloves, clothing, and eye protection P305+P351+P338: If in eyes: Rinse cautiously with water for several minutes P261: Avoid breathing dust P264: Wash hands thoroughly after handling
Serves as a key intermediate for neuroactive tricyclic frameworks.
Utilized in fine-tuning of insecticides and herbicide backbones.
Applied in medicinal chemistry programs requiring fused aromatic pyridines.
Used in structure-activity relationship mapping for ring-closed derivatives.
Store in nitrogen-filled containers, <25°C, protected from light
2 drums high for inert-packed units
Palletized, stretch-wrapped, containerized
Amber glass bottles or foil pouches (10 g to 1 kg)
It’s a core intermediate in CNS, oncology, and anti-inflammatory drug scaffolds, primarily used for structure-building in tricyclic frameworks.
5H,6H,7H,8H,9H-cyclohepta[b]pyridine-5,9-dione
5,9(6H)-Dione, 7,8-dihydro-5H-cyclohepta[b]pyridine and Heterocyclic intermediate with fused pyridine scaffold
It is typically supplied as a non-GMP intermediate for use in early-stage or pilot pharmaceutical programs.
COA, MSDS, and if required, elemental analysis or NMR spectrum can be provided.
Soluble in DMF, DMSO, and moderately in methanol or ethanol; minimal solubility in water.
Yes, with lead time of 2–4 weeks, quantities can range from 10 g lab scale to multi-kg under CRAMS/CDMO engagements.
Typically ≥ 98% by HPLC
COA and MSDS standard; further docs available on request
100% advance for lab quantities; negotiable for scale-up batches
Yes, with proper non-GMP classification and shipment docs
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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