5-Amino oxindole

CAS Number: 120266-80-0

Molecular Formula: C8H8N2O

About 5-Amino oxindole

5-Amino oxindole CAS 120266-80-0 serves as a high purity pharmaceutical intermediate for the custom synthesis of Bruton’s tyrosine kinase (BTK) inhibitors and receptor tyrosine kinase modulators like sunitinib, catering to the growing oncology segment of the API intermediates market. 5-Amino-2-indolinone functions as a...

5-Amino oxindole Specifications

CAS Number

120266-80-0

Molecular Formula

C8H8N2O

Molecular Weight

148.16 g/mol

IUPAC Name

5-amino-1,3-dihydroindol-2-one

Canonical SMILES

C1C2=C(C=CC(=C2)N)NC1=O

InChI Key

JPUYXUBUJJDJNL-UHFFFAOYSA-N

PubChem CID

45595282

CAS Number

120266-80-0

Molecular Formula

C8H8N2O

Molecular Weight

148.16 g/mol

IUPAC Name

5-amino-1,3-dihydroindol-2-one

Canonical SMILES

C1C2=C(C=CC(=C2)N)NC1=O

InChI Key

JPUYXUBUJJDJNL-UHFFFAOYSA-N

PubChem CID

45595282

Molecular Weight

148.16 g/mol

Physical appearance

White to brown powder to crystalline

Pharmaceutical Intermediate

A critical organic building block primarily used as a precursor in the synthesis of various medicinal compounds, including anti-cancer agents, antitumoral agents, and factor Xa inhibitors

Organic Synthesis Building Block

A versatile heterocyclic scaffold and reagent utilized in medicinal chemistry and academic research for the development of bioactive small molecules and the elaboration of complex indolic derivatives

Biological Research Tool

An important reactant used in the study of biochemical pathways, such as Gli1-mediated transcription in the Hedgehog pathway and PKC theta inhibition

Material Science Component

A functionalized indole derivative explored in the creation of new polymers and materials to enhance properties such as conductivity and thermal stability.