Hero Background
rounded-bottom

4-Cyanopyridine (CAS NO : 100-48-1)

4-Cyanopyridine (4CP), or Isonicotinonitrile (CAS 100-48-1), is a critical C6 nitrogen-containing Heterocyclic Building Block indispensable to the synthesis of complex fine chemicals and pharmaceutical actives. As a versatile organic intermediate, 4CP possesses a functional nitrile group (-CN) attached to the C4 position of the pyridine ring, enabling chemists to perform a wide range of transformations. 4CP's primary industrial route is the high-yield Ammoxidation of 4-methylpyridine (4-Picoline). Pyridine-4-carbonitrile's value in the API & CDMO sector is rooted in its role as a direct precursor to Isonicotinic Acid and, most notably, the essential anti-tuberculosis drug Isoniazid (INH). Aside this, Pyridine Carbonitrile is a key reagent in the preparation of the powerful organocatalyst 4-Dimethylaminopyridine (DMAP), a globally preferred coupling agent. 4CP (4-Pyridinecarbonitrile) is produced in pharmaceutical or technical grades by 4-Cyanopyridine manufacturers, ensuring the stringent purity standards (typically > 99%) required for subsequent sensitive synthetic steps. We are the leading 4-Cyanopyridine supplier worldwide ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.

4-Cyanopyridine

4-Cyanopyridine (4CP), or Isonicotinonitrile (CAS 100-48-1), is a critical C6 nitrogen-containing Heterocyclic Building Block indispensable to the synthesis of complex fine chemicals and pharmaceutical actives. As a versatile organic intermediate, 4CP possesses a functional nitrile group (-CN) attached to the C4 position of the pyridine ring, enabling chemists to perform a wide range of transformations. 4CP's primary industrial route is the high-yield Ammoxidation of 4-methylpyridine (4-Picoline). Pyridine-4-carbonitrile's value in the API & CDMO sector is rooted in its role as a direct precursor to Isonicotinic Acid and, most notably, the essential anti-tuberculosis drug Isoniazid (INH). Aside this, Pyridine Carbonitrile is a key reagent in the preparation of the powerful organocatalyst 4-Dimethylaminopyridine (DMAP), a globally preferred coupling agent. 4CP (4-Pyridinecarbonitrile) is produced in pharmaceutical or technical grades by 4-Cyanopyridine manufacturers, ensuring the stringent purity standards (typically > 99%) required for subsequent sensitive synthetic steps. We are the leading 4-Cyanopyridine supplier worldwide ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.

Industries 1Industries

Industry

Pharmaceutical

Category 1Category

Category

Pharmaceutical Actives & Precursors

Sub-categorySub-category 1

Sub-category

Intermediates & Precursors

Get a Quote

Details included in quote

Minimum Order Quantity

Lead Time

Regional Availability

Incoterms

Intersect 1
Rounded Top

Chemical Properties & Specifications

Applications of 4-Cyanopyridine

Pharmaceuticals

Key Intermediate in the synthesis of a variety of drugs. The nitrile (-CN) group is readily hydrolyzed to a carboxylic acid (-COOH) or reduced to an amine (-CH2NH2)

Fine & Specialty Chemicals

Precursor for the synthesis of complex pyridine derivatives, including the powerful nucleophilic catalyst 4-Dimethylaminopyridine (DMAP)

Agrochemicals

Intermediate in the development of certain pesticides and herbicides that incorporate the pyridine ring structure.

Have Questions About 4-Cyanopyridine?
We've Got Answers.

Get a Quote

Get a Quote