Search through
4-Cyanopyridine (4CP), or Isonicotinonitrile (CAS 100-48-1), is a critical C6 nitrogen-containing Heterocyclic Building Block indispensable to the synthesis of complex fine chemicals and pharmaceutical actives. As a versatile organic intermediate, 4CP possesses a functional nitrile group (-CN) attached to the C4 position of the pyridine ring, enabling chemists to perform a wide range of transformations. 4CP's primary industrial route is the high-yield Ammoxidation of 4-methylpyridine (4-Picoline). Pyridine-4-carbonitrile's value in the API & CDMO sector is rooted in its role as a direct precursor to Isonicotinic Acid and, most notably, the essential anti-tuberculosis drug Isoniazid (INH). Aside this, Pyridine Carbonitrile is a key reagent in the preparation of the powerful organocatalyst 4-Dimethylaminopyridine (DMAP), a globally preferred coupling agent. 4CP (4-Pyridinecarbonitrile) is produced in pharmaceutical or technical grades by 4-Cyanopyridine manufacturers, ensuring the stringent purity standards (typically > 99%) required for subsequent sensitive synthetic steps. We are the leading 4-Cyanopyridine supplier worldwide ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.
4-Cyanopyridine (4CP), or Isonicotinonitrile (CAS 100-48-1), is a critical C6 nitrogen-containing Heterocyclic Building Block indispensable to the synthesis of complex fine chemicals and pharmaceutical actives. As a versatile organic intermediate, 4CP possesses a functional nitrile group (-CN) attached to the C4 position of the pyridine ring, enabling chemists to perform a wide range of transformations. 4CP's primary industrial route is the high-yield Ammoxidation of 4-methylpyridine (4-Picoline). Pyridine-4-carbonitrile's value in the API & CDMO sector is rooted in its role as a direct precursor to Isonicotinic Acid and, most notably, the essential anti-tuberculosis drug Isoniazid (INH). As...
Chemical Properties & Specifications
H302 (94.9%): Harmful if swallowed
H312 (58.2%): Harmful in contact with skin
H319 (43%): Causes serious eye irritation
H332 (58.2%): Harmful if inhaled
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P321, P330, P337+P317, P362+P364, and P501
Key Intermediate in the synthesis of a variety of drugs. The nitrile (-CN) group is readily hydrolyzed to a carboxylic acid (-COOH) or reduced to an amine (-CH2NH2)
Precursor for the synthesis of complex pyridine derivatives, including the powerful nucleophilic catalyst 4-Dimethylaminopyridine (DMAP)
Intermediate in the development of certain pesticides and herbicides that incorporate the pyridine ring structure.
An important fine chemical intermediate used in the synthesis of antidepressants, antiviral drugs, anti-tuberculosis medications like isoniazid, and the gout treatment drug topiroxostat
A building block used for the preparation of isonicotinic acid and 4-dimethylaminopyridine (DMAP)
A key structural unit used in the development of pesticides and herbicides
A precursor used in the manufacturing of specialty dyes, functional polymers, and catalyst ligands
No. 4-Cyanopyridine is classified as a highly critical Pharmaceutical Intermediate or a Heterocyclic Building Block, but it is not an Active Pharmaceutical Ingredient.
Main use is the synthesis of Isoniazid (INH), a crucial anti-tuberculosis agent, and the highly selective organocatalyst DMAP (4- Dimethylaminopyridine).
Isoniazid (INH) (Anti-Tuberculosis drug), Topiroxostat (Gout medication), Fampridine (Multiple Sclerosis drug), and various HDAC inhibitors.
DMAP (Catalyst), specialty dyes, and agrochemicals.
Various Agro actives and their related intermediates.
4-Cyanopyridine (4-CP), also known as Isonicotinonitrile, is a critical heterocyclic building block used as an intermediate in the synthesis of pharmaceuticals like Isoniazid, Topiroxostat, and Bromazepam, as well as agrochemicals and catalysts like DMAP
This compound is widely used in the pharmaceutical, agrochemical, and fine chemical industries for the production of medicines, pesticides, and specialty reagents
It is soluble in water, alcohols, ethanol, ether, and benzene, and is typically used in organic synthesis and catalytic protocols
Standard specifications include CAS number 100-48-1, high purity (typically >=99%), and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
Description : Calcium acetate monohydrate (CAS No: 5743-26-0) occupies a critical position in the global specialit...
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...
