4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one, commonly known as Tetralone, is an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. Tetralone serves as a key building block in the pharmaceutical manufacturing process of Sertraline.
4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one, commonly known as Tetralone, is an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. Tetralone serves as a key building block in the pharmaceutical manufacturing process of Sertraline.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Reactive Hazard: None known, based on information available Stability: Stable under normal conditions. Conditions to Avoid: Incompatible products. Excess heat. Incompatible Materials: Strong oxidizing agents Hazardous Decomposition Products: Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization: Not occured Hazardous Reactions: None under normal processing.
Persistence and Degradability: Insoluble in water Persistence is unlikely based on information available.
Carbon monoxide (CO). Carbon dioxide (CO2).
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.
Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.
Prevention Wash face, hands and any exposed skin thoroughly after handling Do not eat , drink or smoke when using this product Avoid breathing dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area
Used as an intermediate in the synthesis of Sertraline.
Serves in the development of other bioactive molecules and as a reference standard in analytical studies.
Use only under a chemical fume hood. Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation.
Keep containers tightly closed in a dry, cool and well-ventilated place. Incompatible Materials. Strong oxidizing agents.
Available in various laboratory-scale quantities for synthesis and analysis
CAS No. : 446292-07-5
CAS No. : 504-02-9
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description: Cyclohexane-1,3-dione is a cyclohexanedione carrying oxo substituents at positions 1 and 3. It is a ...
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