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3-(4-Chlorophenyl)Isoindolin-1-one

3-(4-Chlorophenyl)Isoindolin-1-one

CAS Number: 2224-77-3

Molecular Formula: C14H10ClNO

High Purity Isoindolin-1-one Building BlockChlorthalidone Impurity Standard 2224-77-3Intermediate: Chlorthalidone & MazindolAnalytical Standards Diuretic Related Compounds

About 3-(4-Chlorophenyl)Isoindolin-1-one

Our 3-(4-Chlorophenyl)Isoindolin-1-one is a high-purity crystalline intermediate belonging to the isoindolinone family. This compound is an essential "platform molecule" used in the multi-step synthesis of various tricyclic sympathomimetic agents, most notably Mazindol. Specialised heterocyclic organic building block p...

3-(4-Chlorophenyl)Isoindolin-1-one Specifications

CAS Number
2224-77-3
Molecular Formula
C14H10ClNO
Molecular Weight
243.69
IUPAC Name
3-(4-chlorophenyl)-2,3-dihydroisoindol-1-one
Canonical SMILES
C1=CC=C2C(=C1)C(NC2=O)C3=CC=C(C=C3)Cl
InChI Key
OMUHBVDRMKRVLW-UHFFFAOYSA-N
InChI
1S/C14H10ClNO/c15-10-7-5-9(6-8-10)13-11-3-1-2-4-12(11)14(17)16-13/h1-8,13H,(H,16,17)
PubChem CID
5073852
HSN No
29337900
Molecular Weight
243.69
Melting Point (Experimental)
213-215°C
Boiling Point (Predicted)
444.786±45.00 °C
Press: 760.00 Torr Density (Predicted)
1.302±0.06 g/cm3 Temp: 25°C; Press: 760 Torr
pKa (Predicted)
13.938±0.40 Most Acidic Temp: 25°C
Hazard Classes and Categories
Eye Dam. 1 (100%)
Precautionary Statement Codes
P264+P265, P280, P305+P354+P338, and P317

API

Primary intermediate for the synthesis of Mazindol and related appetite suppressants

Impurity Profiling

Reference standard (Impurity/Related Compound) for Chlorthalidone and other isoindoline-based diuretics

Drug Discovery & Research

Scaffold in medicinal chemistry for developing new anti-arrhythmic, antimicrobial, and antipsychotic agents

Reference Standards

Utilized in its deuterium-labeled form (d₄) as an internal standard for quantitative analysis by GC-MS and LC-MS.

Storage Conditions

2°C – 8°C (Refrigerator) for long-term stability

COA
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3-(4-Chlorophenyl)Isoindolin-1-one FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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