2-(Piperidin-4-YL)-1H-benzo[D]imidazole

CAS Number: 38385-95-4

Molecular Formula: C12H15N3

About 2-(Piperidin-4-YL)-1H-benzo[D]imidazole

2-(Piperidin-4-yl)-1H-benzimidazole CAS 38385-95-4 acts as a critical building block in the API intermediates market, specifically for the synthesis of Bilastine and novel anti-inflammatory agents, requiring >= 99% pharma-grade purity to meet stringent ICH guidelines. 2-(4-Piperidyl)-1H-benzoimidazole serves the high p...

Variants

2-(PIPERIDIN-4-YL)-1H-BENZOIMIDAZOLE

CAS: 38385-95-4

Synonyms

38385-95-4
2-Piperidin-4-yl-1H-benzoimidazole
2-(PIPERIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE
2-piperidin-4-yl-1H-benzimidazole
2-(4-piperidinyl)-1H-benzimidazole

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2-(Piperidin-4-YL)-1H-benzo[D]imidazole Specifications

CAS Number

38385-95-4

Molecular Formula

C12H15N3

Molecular Weight

201.27 g/mol

IUPAC Name

2-piperidin-4-yl-1H-benzimidazole

Canonical SMILES

C1CNCCC1C2=NC3=CC=CC=C3N2

InChI Key

HBOGHPAOOWUTLB-UHFFFAOYSA-N

InChI

InChI=1S/C12H15N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,15)

CAS Number

38385-95-4

Molecular Formula

C12H15N3

Molecular Weight

201.27 g/mol

IUPAC Name

2-piperidin-4-yl-1H-benzimidazole

Canonical SMILES

C1CNCCC1C2=NC3=CC=CC=C3N2

InChI Key

HBOGHPAOOWUTLB-UHFFFAOYSA-N

InChI

InChI=1S/C12H15N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,15)

Molecular Weight

201.27 g/mol

Physical appearance

White to light yellow to light orange powder to crystal

Pharmaceutical Intermediate

A key building block utilized as a reagent in the synthesis of various medicinal compounds, including anti-inflammatory agents, sodium channel blockers for ischemic stroke treatment, and Akt1/Akt2 dual inhibitors for oncology research

Chemical Research Reagent

A versatile heterocyclic scaffold employed in the development of complex organic molecules and used in biochemical assays to study receptor interactions and signaling pathways

Anti-Inflammatory Lead Compound

A privileged structure used to design and synthesize derivatives that inhibit nitric oxide and TNF-α production in macrophages

Neurological Drug Candidate

A critical starting material in the synthesis of pharmaceuticals targeting neurological disorders and dopamine/5-HT1A receptor modulators for schizophrenia research.