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2-Methylpyridine (CAS NO : 109-06-8)

2-Methylpyridine (CAS No: 109-06-8), also known as 2-picoline, is a vital heterocyclic intermediate primarily utilised in the production of 2-vinylpyridine for the rubber industry and the nitrogen fertiliser synergist nitrapyrin. The compound's reactive methyl group facilitates the synthesis of critical agrochemicals like the herbicide 4-amino-3,5,6-trichloropyridine, as well as pharmaceutical agents including amprolium, picoplatin, and the organophosphorus antidote pralidoxime chloride. While traditionally derived from coal tar or synthesised via gas-phase reactions of acetaldehyde and ammonia, modern industrial advancements focus on cobalt-catalysed trimerisation of acetonitrile and acetylene to achieve high regioselectivity and yields exceeding 90%. As a globally established 2-Methylpyridine supplier with 2-Methylpyridine purity 99.9%, we ensure dependable supply, consistent quality, and complete regulatory documentation, including 2-Methylpyridine CoA and 2-Methylpyridine TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination.

2-Methylpyridine

Variants | Grades | Strengths

2-Methylpyridine (CAS No: 109-06-8), also known as 2-picoline, is a vital heterocyclic intermediate primarily utilised in the production of 2-vinylpyridine for the rubber industry and the nitrogen fertiliser synergist nitrapyrin. The compound's reactive methyl group facilitates the synthesis of critical agrochemicals like the herbicide 4-amino-3,5,6-trichloropyridine, as well as pharmaceutical agents including amprolium, picoplatin, and the organophosphorus antidote pralidoxime chloride. While traditionally derived from coal tar or synthesised via gas-phase reactions of acetaldehyde and ammonia, modern industrial advancements focus on cobalt-catalysed trimerisation of acetonitrile and acetyl...

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Chemical Properties & Specifications

Applications of 2-Methylpyridine

Chemical Intermediate

A chemical intermediate for the synthesis of vinylpyridine and the agrichemical nitrapyrin

Pharmaceutical Building Block

A building block in the synthesis of various pharmaceutical compounds such as amprolium, picoplatin, dimethindene, and encainide

Agricultural Formulation

A compound used in the formulation of agrochemicals, including pesticides, herbicides, and nitrogen fertilizer synergists like 2-chloro-6-(trichloromethyl)pyridine

Industrial Solvent

A solvent in chemical reactions that enhances reaction rates and product yields in industrial processes

Corrosion Inhibitor Production

A compound employed in the production of corrosion inhibitors to protect metals in the construction and automotive industries

Flavor and Fragrance Formulation

A compound utilized in the formulation of flavors and fragrances to offer unique aromatic properties

Synthetic Reagent

A reagent used in synthetic pathways for the production of dearomatized, allylated, and C-H bond activated pyridine derivatives

Scientific Research

A compound used to study the electron and proton transfer reactions of lumiflavin using Fourier transform ion cyclotron resonance mass spectrometry

Have Questions About 2-Methylpyridine?
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2-Methylpyridine, also known as 2-picoline, is a colorless organic liquid and a derivative of pyridine. It is primarily used as a precursor to synthesize 2-vinylpyridine for the rubber industry and the agrichemical nitrapyrin, and it also serves as an intermediate for various pharmaceuticals like amprolium and niacin

This compound is widely utilized in the pharmaceutical, agrochemical, polymer, rubber, and flavor and fragrance industries

2-Methylpyridine is a versatile solvent and building block that is completely soluble in water, alcohol, and ether

Standard analytical specifications include a CAS number of 109-06-8, a purity of ≥98%, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, and lead times for international customers depend on the shipping destination and specific requirements.

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