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2-Iodoacetamide

2-Iodoacetamide

CAS Number: 144-48-9

Molecular Formula: C2H4INO

About 2-Iodoacetamide

2-Iodoacetamide CAS 144-48-9 is a paramount sulfhydryl alkylating agent in the API intermediates market, where its ability to irreversibly inhibit cysteine peptidases through covalent bonding makes it a cornerstone for high purity fine chemicals used in targeted enzyme inhibition studies. As a leading bulk chemical sup...

2-Iodoacetamide Specifications

CAS Number

144-48-9

Molecular Formula

C2H4INO

Molecular Weight

184.96 g/mol

IUPAC Name

2-iodoacetamide

Canonical SMILES

NC(=O)CI

InChI Key

PGLTVOMIXTUURA-UHFFFAOYSA-N

CAS Number

144-48-9

Molecular Formula

C2H4INO

Molecular Weight

184.96 g/mol

IUPAC Name

2-iodoacetamide

Canonical SMILES

NC(=O)CI

InChI Key

PGLTVOMIXTUURA-UHFFFAOYSA-N

Molecular Weight

184.96 g/mol

Cysteine Alkylating Agent

A commonly used reagent for the alkylation of cysteine residues during protein sample preparation for proteomics and de novo peptide sequencing to prevent the formation of disulfide bonds

Enzyme Inhibitor

An irreversible inhibitor of various enzymes, including cysteine peptidases and deubiquitinase enzymes (DUBs), by covalently binding to the catalytic cysteine residue at the active site

Glycolysis Inhibitor

A chemical agent used in metabolic studies to inhibit glycolysis by inactivating the enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Organic Synthesis Building Block

A functionalized organic compound used as an electrophile for the covalent modification of nucleophilic residues on proteins such as methionine and histidine in biochemical research.

2-Iodoacetamide FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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