

2,4-Thiazolidinedione (CAS 2295-31-0) is a pivotal heterocyclic building block in the API intermediates market, primarily utilized for the synthesis of glitazone-class antidiabetic agents and novel oncology therapeutics where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are required to maintain strict impurity profiles. 2,4-Diketothiazolidine serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that offer rigorous analytical validation and regulatory compliance to support complex drug development pipelines. Thiazolidine-2,4-dione remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing while ensuring consistent crystalline morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 2,4-Thiazolidinedione COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

2,4-Thiazolidinedione (CAS 2295-31-0) is a pivotal heterocyclic building block in the API intermediates market, primarily utilized for the synthesis of glitazone-class antidiabetic agents and novel oncology therapeutics where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are required to maintain strict impurity profiles. 2,4-Diketothiazolidine serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that offer rigorous analytical validation and regulatory compliance to support complex drug development pipelines. Thiazolidine-2,4-dione remains a preferred choice for ...

Chemical Properties & Specifications
P261, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, and P501
Skin Sens. 1 (96.4%)
Eye Irrit. 2A (100%)
A versatile scaffold and key building block used in the synthesis of various bioactive derivatives and active pharmaceutical ingredients, including FDA-approved glitazones like pioglitazone and rosiglitazone
A primary therapeutic pharmacophore that acts as a PPAR-gamma agonist to increase insulin sensitivity, enhance glucose uptake, and manage type 2 diabetes mellitus
A privileged sulfur-containing heterocyclic motif utilized in medicinal chemistry research to develop compounds with antimicrobial, anticancer, anti-inflammatory, and antioxidant activities
A functional agent reported for use as a corrosion inhibitor for steel in acidic environments and as a brightener within the electroplating industry.
2,4-Thiazolidinedione, also known as TZD, is a heterocyclic compound that serves as a privileged scaffold in medicinal chemistry, primarily used as an insulin-sensitizing agent for the management of type 2 diabetes mellitus
This compound is predominantly used in the pharmaceutical and agrochemical industries for the development of antidiabetic drugs, as well as antimicrobial, anti-inflammatory, and antioxidant agents
It is compatible with oral tablet formulations, often as monotherapy or in combination with other agents like metformin, and is also utilized in various liquid-phase synthetic protocols
Standard analytical specifications include CAS number 2295-31-0, high purity levels, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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