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2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) acts as a pivotal building block in the API intermediates market, primarily serving as the essential precursor for the synthesis of Canagliflozin, an SGLT2 inhibitor for type 2 diabetes management. As a premier bulk chemical supplier, we note that CDMOs are increasingly focusing on high-purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) to ensure optimal yields and minimize downstream processing hurdles in complex organic synthesis. 2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) has experienced significant shifts in global sourcing as manufacturers demand custom synthesis services that offer rigorous analytical validation and robust impurity profiling to satisfy stringent international regulatory compliance. This trend emphasizes the industry's move toward securing reliable, high-performance chemical precursors that can withstand intensive audit processes and support large-scale commercial manufacturing. Thiophene, 2-(4-fluorophenyl)- (CAS 58861-48-6) remains the preferred choice for advanced process development where maintaining precise crystalline morphology and specific particle size is critical for consistent reactivity and final product stability. To address these evolving technical requirements, suppliers are implementing optimized Kumada and Suzuki coupling protocols to deliver consistent batches (Pharma/API purity 99% | General Industry purity 98%), aligning with global sustainability initiatives and the necessity for high-purity building blocks that guarantee clinical efficacy. We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API. We offer a broad range of pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical support (HPLC/NMR/MS), 2-(4-Fluorophenyl)thiophene COA/TDS/SDS, region-specific regulatory support, reliable lead times, and worldwide supply chain capabilities.
2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) acts as a pivotal building block in the API intermediates market, primarily serving as the essential precursor for the synthesis of Canagliflozin, an SGLT2 inhibitor for type 2 diabetes management. As a premier bulk chemical supplier, we note that CDMOs are increasingly focusing on high-purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) to ensure optimal yields and minimize downstream processing hurdles in complex organic synthesis. 2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) has experienced significant shifts in global sourcing as manufacturers demand custom synthesis services that offer rigorous analytical validation an...
Chemical Properties & Specifications
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Acute Tox. 4 (100%)
Skin Irrit. 2 (50%)
A key synthetic building block primarily utilized in the production of the SGLT2 inhibitor canagliflozin for the treatment of type 2 diabetes
A fluorinated thiophene derivative employed in cross-coupling reactions to develop complex heterocyclic molecules with potential pharmacological properties
A specialized material used in medicinal chemistry to study structure-activity relationships, particularly regarding the influence of fluorine on metabolic stability and lipophilicity.
2-(4-Fluorophenyl)thiophene is a thiophene derivative that serves as a crucial building block and key pharmaceutical intermediate, most notably used in the synthesis of the SGLT2 inhibitor Canagliflozin for treating type 2 diabetes
This compound is primarily used in the pharmaceutical and agrochemical industries, as well as in material science for developing advanced polymers and specialty coatings
It is a white to light orange solid at room temperature that becomes liquid upon heating and is soluble in organic solvents like methanol, dichloromethane, and ethyl acetate
Standard specifications include CAS number 58861-48-6, a purity of typically 95% or higher, melting point of 51-55°C, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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