2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid

CAS Number: 594839-88-0

Molecular Formula: C14H7Cl2NO3

About 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid

2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid CAS 94790-37-1 is a highly specialized small molecule utilised as the primary active pharmaceutical ingredient for the kinetic stabilization of transthyretin to treat TTR amyloidosis, maintaining a pharma purity of >= 99% to meet rigorous FDA and EMA standards. As a c...

2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid Specifications

CAS Number

594839-88-0

Molecular Formula

C14H7Cl2NO3

Molecular Weight

308.12 g/mol

IUPAC Name

2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid

Canonical SMILES

C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl

InChI Key

TXEIIPDJKFWEEC-UHFFFAOYSA-N

PubChem CID

11001318

CAS Number

594839-88-0

Molecular Formula

C14H7Cl2NO3

Molecular Weight

308.12 g/mol

IUPAC Name

2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid

Canonical SMILES

C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl

InChI Key

TXEIIPDJKFWEEC-UHFFFAOYSA-N

PubChem CID

11001318

Molecular Weight

308.12 g/mol

Physical appearance

White to off-white solid

Pharmaceutical Intermediate

An important building block and active pharmaceutical ingredient known as Tafamidis, specifically utilized as a transthyretin stabilizer in the treatment of cardiomyopathy associated with wild-type or hereditary transthyretin-mediated amyloidosis (ATTR)

Pharmaceutical Standard

A high-purity reference material employed as a certified standard for analytical testing, quality control, and pharmacokinetic studies in drug development

Organic Synthesis Building Block

A functionalized benzoxazole derivative used in medicinal chemistry research for the development of complex heterocyclic molecules and novel therapeutic agents.