Search through
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride

CAS Number: 1841081-72-8

Molecular Formula: C16H24ClN3O

Purity: 97% 1-(2-ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride

API: BilastineBilastine IntermediateAK174349

About 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride (CAS No: 1841081-72-8) represents a critical benzimidazole-piperidine hybrid scaffold primarily utilised as a high-purity synthetic intermediate in the production of Bilastine, a second-generation non-sedating H1-antihistamine. The molecule's strat...

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride Specifications

CAS Number
1841081-72-8
Molecular Formula
C16H24ClN3O
Molecular Weight
309.83 g/mol
IUPAC Name
1-(2-ethoxyethyl)-2-piperidin-4-ylbenzimidazole;hydrochloride
Canonical SMILES
CCOCCN1C2=CC=CC=C2N=C1C3CCNCC3.Cl
InChI Key
YOWRIDDXDCHTLL-UHFFFAOYSA-N
InChI
1S/C16H23N3O.ClH/c1-2-20-12-11-19-15-6-4-3-5-14(15)18-16(19)13-7-9-17-10-8-13;/h3-6,13,17H,2,7-12H2,1H3;1H
EINECS Number
260-968-7
MDL Number
MFCD29044890
HSN No
38229010
Molecular Weight
309.83 g/mol
PSA
39.080
LogP
3.67060
Compound Is Canonicalized
True
Monoisotopic Mass
309.1607901
Complexity
293
Rotatable Bond Count
5
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Topological Polar Surface Area
39.1
Heavy Atom Count
21
Purity
97% 1-(2-ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride
Physical appearance
White solid
Freezing point
177.9ºC at 760mmHg
pKa
10.02±0.10
Precise Quality
≥98.0%
Hazard Codes
Xn
Signal Word
Warning
Risk Statements
R62;R63
Safety Statements
S26;S36
Hazard Declaration
H361
RTECS
DE2275900
Risk Statements
R62: Risk of impaired fertility R63: Possible risk of harm to the unborn child.
Precautionary Statement Codes
P261, P305+P351+P338
Hazard Classes and Categories
Acute Tox. 4 (100%), Skin Irrit. 2 (100%), Eye Irrit. 2 (100%), STOT SE 3 (100%)

Pharmaceutical Intermediate

An impurity of Bilastine used for the symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria

Synthetic Intermediate

A pharmaceutical-grade synthetic intermediate for Mirabegron process development to support regulatory submission

Research Chemical

A useful research chemical for laboratory research purposes and a range of applications in synthetic organic chemistry and pharmaceutical analysis

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

Rounded Top

Explore Pharmaceutical Portfolio

Calcium acetate monohydrate

CAS No : 5743-26-0

Calcium acetate monohydrate

Category : Pharmaceutical Actives & Precursors

Sub-Category : Active Pharmaceutical Ingredients (APIs)

Description : Calcium acetate monohydrate (CAS No: 5743-26-0) occupies a critical position in the global specialit...

View Product
Magnesium Sulphate Monohydrate

CAS No : 14168-73-1

Magnesium Sulphate Monohydrate

Category : Pharmaceutical Actives & Precursors, Inorganic Chemicals

Sub-Category : Active Pharmaceutical Ingredients (APIs), Inorganic Salts

Description : We supply high-efficiency magnesium sulphate monohydrate (CAS No: 14168-73-1) archieved across inter...

View Product
P-Nitrobenzoyl Chloride

CAS No : 122-04-3

P-Nitrobenzoyl Chloride

Category : Pharmaceutical Actives & Precursors

Sub-Category : Intermediates & Precursors

Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...

View Product
3-(4 Chloro Phenyl) Glutaric Acid

CAS No : 35271-74-0

Category : Pharmaceutical Actives & Precursors

Sub-Category : Active Pharmaceutical Ingredients (APIs)

Description : 3-(4-Chlorophenyl)glutaric acid (CAS 35271-74-0) is a pivotal building block in the API intermediate...

View Product