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Trimethylsulfoxonium iodide (CAS 1774-47-6) is an essential reagent in the API intermediates market, serving as the primary precursor for dimethyloxosulfonium methylide used in Corey-Chaykovsky cyclopropanation and epoxidation. As a leading bulk chemical supplier, we observe that CDMOs are increasingly integrating these high-purity fine chemicals into their specialized synthetic toolkits to produce complex heterocyclic scaffolds for oncology and antiviral therapeutics (Pharma/API purity 99%). Trimethyloxosulfonium iodide (CAS 1774-47-6) remains a critical building block for the synthesis of azole antifungals, such as fluconazole, where stereoselective methylene transfer is paramount. Current global sourcing shifts favor manufacturers who provide robust custom synthesis services and maintain rigorous regulatory compliance to meet the evolving ICH Q3A(R2) impurity profile standards (Pharma/API purity 99%). Sulfoxonium, trimethyl-, iodide (1:1) (CAS 1774-47-6) is gaining traction in industrial use for the development of advanced ionic liquids and as a selective methylating agent in polymer science. Reliability in the supply chain for these high-purity fine chemicals is essential as the industry moves toward sustainable green chemistry and optimized atom-efficient processes (General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting trimethylsulfoxonium iodide COA/TDS/SDS region-specific regulatory support, reliable lead times, and worldwide supply chain capabilities.
Trimethylsulfoxonium iodide (CAS 1774-47-6) is an essential reagent in the API intermediates market, serving as the primary precursor for dimethyloxosulfonium methylide used in Corey-Chaykovsky cyclopropanation and epoxidation. As a leading bulk chemical supplier, we observe that CDMOs are increasingly integrating these high-purity fine chemicals into their specialized synthetic toolkits to produce complex heterocyclic scaffolds for oncology and antiviral therapeutics (Pharma/API purity 99%). Trimethyloxosulfonium iodide (CAS 1774-47-6) remains a critical building block for the synthesis of azole antifungals, such as fluconazole, where stereoselective methylene transfer is paramount. Current...
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Industrial Chemicals
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Organic Intermediates
Chlorinated Aromatic Compounds
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Chemical Properties & Specifications
P261, P264, P264+P265, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501
Acute Tox. 5 (17%)
Skin Irrit. 2 (61.7%)
Trimethylsulfoxonium Iodide is a crucial reagent in the Corey-Chaykovsky reaction used to prepare epoxide intermediates and cyclopropane derivatives, which are essential building blocks for complex pharmaceutical molecules and bioactive peptides
It serves as a powerful methylene-transfer and methylating agent, facilitating the introduction of methyl groups and the synthesis of sulfoxides and sulfones in academic and industrial laboratories
The compound is utilized in the production of agrochemicals, fine chemicals, and advanced materials like polymers to enhance thermal stability and chemical resistance.
Trimethylsulfoxonium Iodide is a sulfoxonium salt and organosulfur compound used primarily as a methylene-transfer reagent to prepare epoxides from ketones and aldehydes, and as a powerful methylating agent in organic synthesis
This compound is widely used in the pharmaceutical, agrochemical, biotechnology, and material science industries for drug development and chemical research
It is compatible with water, alcohols, and polar organic solvents, and is typically reacted with strong bases like sodium hydride to form reactive ylides
Standard specifications include CAS number 1774-47-6, purity ≥98%, molecular weight 220.07, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the specific shipping destination and order volume.
