

PTSU (Tosylurea), is a specialised organic compound that bridges the gap between sulfonyl chemistry and urea-based synthesis. Within the Pharmaceutical, Agrochemical, and Industrial Chemical hierarchies, serves as a high-value building block for the construction of complex heterocyclic rings. Unique molecular architecture - featuring a stable tosyl (Ts) group and a reactive urea functionality - makes it an indispensable intermediate for the synthesis of sulfonylurea-class drugs and highly selective herbicides. Source High-Purity Para Toluene Sulphonyl Urea from Scimplify, a premier global manufacturer and wholesale supplier of sulfonylurea intermediates. Our PTSU is a premium-grade organic building block engineered for the synthesis of next-generation sulfonylurea herbicides and anti-diabetic pharmaceuticals. As an authoritative PTSU manufacturer, we provide a material characterised by its high crystalline stability and low moisture profile, essential for CDMOs and large-scale industrial chemical synthesis. Whether you are developing selective crop protection agents or advanced sulfonylurea-based APIs, our p-Toluenesulfonylurea offers the reactive consistency, global regulatory compliance, and reliable bulk lead times required for global supply chain excellence. Our facility ensures strict adherence to quality protocols, delivering the high-assay material required for complex multi-step organic transformations.


PTSU (Tosylurea), is a specialised organic compound that bridges the gap between sulfonyl chemistry and urea-based synthesis. Within the Pharmaceutical, Agrochemical, and Industrial Chemical hierarchies, serves as a high-value building block for the construction of complex heterocyclic rings. Unique molecular architecture - featuring a stable tosyl (Ts) group and a reactive urea functionality - makes it an indispensable intermediate for the synthesis of sulfonylurea-class drugs and highly selective herbicides. Source High-Purity Para Toluene Sulphonyl Urea from Scimplify, a premier global manufacturer and wholesale supplier of sulfonylurea intermediates. Our PTSU is a premium-grade organic b...
Pharmaceutical
Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Acute Tox. 4 (28.6%)
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Critical precursor for the synthesis of oral hypoglycemic agents (anti-diabetics) such as Tolbutamide. Sulfonylurea moiety is the pharmacophore responsible for stimulating insulin secretion from pancreatic beta cells
Production of sulfonylurea herbicides, which are known for their low application rates and high selectivity. These herbicides work by inhibiting the ALS (acetolactate synthase) enzyme in weeds, effectively stopping plant growth without harming major cereal crops.
Functional intermediate, to introduce the toluene-sulfonamide structure into specialized resins and polymers, enhancing thermal stability and providing specific chemical resistance in specialty coatings
Stable under normal temperatures; however, it should be protected from strong bases which can cause hydrolysis of the urea linkage
Store in a cool, dry, well-ventilated area. Keep containers tightly closed
Recommended storage: 15°C to 25°C
Non-hazardous for transport in standard crystalline form; available in 25kg fiber drums with double PE liners for international B2B supply